摘要
《2019年欧洲抗风湿病联盟系统性红斑狼疮管理指南》是欧洲抗风湿病联盟自2007年以来,第二次针对系统性红斑狼疮(systemic lupus erthymatosus,SLE)整体管理制定的指南。该指南对SLE的治疗策略、治疗目标、激素方案选择、狼疮性肾炎"多靶点"治疗以及生物制剂应用等内容进行了更新,在达标治疗的大趋势下,为SLE如此复杂的疾病,指明了治疗方向。本文对指南更新内容进行详细解读,以期为SLE临床诊治提供借鉴。
2019 update of the EULAR recommendations for the management of systemic lupus erythematosus is the second edition that EULAR has developed for the general management of systemic lupus erythematosus(SLE)since 2007.The treatment strategy,validated goals of treatment,alternative regimens of glucocorticoids,"multi-targeted"therapy in lupus nephritis,and biological therapy for SLE were updated in the recommendations,which indicated the direction for the treatment of SLE.A detailed interpretation of the updated guidelines is provided in this article,aiming to provide references for the clinical diagnosis and treatment of SLE.
作者
季兰岚
张卓莉
JI Lan-lan;ZHANG Zhuo-li(Department of Rheumatology and Immunology,Peking University First Hospital,Beijing 100034,China)
出处
《协和医学杂志》
CSCD
2020年第3期283-288,共6页
Medical Journal of Peking Union Medical College Hospital
关键词
系统性红斑狼疮
指南
达标
systemic lupus erythematosus
recommendation
treat to target
