指南的系统评价:是什么,为什么,怎么做

Systematic Review of Clinical Practice Guidelines:What,Why and How

近年来,临床实践指南的数量快速增长,越来越多相同或相似的指南被制订和发表,这些指南在方法学质量和推荐意见等方面存在一定差异和冲突,临床工作人员在使用指南的过程中面临诸多困惑。通过对指南进行系统评价,能够全面、客观地呈现某一领域或具体临床问题所有相关指南的现状和差异,更好地指导临床实践,提升医疗服务质量。本文针对指南系统评价的定义、方法及存在的挑战展开讨论,并就如何开展指南系统评价研究提出思考与建议,供指南的制订者、使用者和研究者参考。

In recent years,the number of clinical practice guidelines has been growing rapidly.An increasing number of identical or similar guidelines on the same topic have been developed and published for diseases.There are certain differences or conflicts in methodological quality and contents of recommendation.Clinical staffs face a lot of confusion when using the guidelines.A systematic review of guidelines can present more comprehensively and objectively the current status and differences in guidelines on the same topic,and can better guide clinical practice and improve the quality of healthcare service.Thus,we discussed the definition,methods,and challenges in systematic review of guidelines,and put forward some suggestions on how to develop a systematic review of guidelines,so as to provide references for guideline developers,users,and researchers.