合并慢性代谢性基础疾病的新型冠状病毒肺炎病人临床分析

Clinical characteristics analysis of 24 COVID-19 patients with chronic metabolic underlying diseases

目的:分析慢性代谢性基础疾病对新型冠状病毒肺炎(COVID-19)的可能影响,探讨治疗COVID-19的措施。方法:对合并慢性代谢性基础疾病的24例COVID-19普通型和重型病例的基础性疾病情况、临床表现、实验室检查等进行回顾性分析。结果:COVID-19病人多合并高血压、糖尿病等慢性代谢性基础疾病,多数重型组病人合并多种基础性疾病,症状加重,可能并发细菌感染、心肌损伤等。重型组病人胸闷发生率、白蛋白降低率高于普通型组,差异有统计学意义(P <0. 01和P <0. 05)。结论:COVID-19病情发展快,多变,治疗时需密切关注病人慢性代谢性基础疾病的发展变化,同时防止细菌感染、心肌损伤等的发生,对促进病人转归有重要意义。

Objective:To analyze the effects of the chronic metabolic underlying diseases on corona virus disease 2019(COVID-19),and explore the possible measures to predict and ameliorate COVID-19.Methods:The basic diseases,clinical manifestations and laboratory examinations in 24 normal and severe COVID-19 patients complicated with chronic metabolic basic diseases were analyzed retrospectively.Results:The COVID-19 patients were mostly associated with chronic metabolic basic diseases such as hypertension and diabetes,and most patients in the severe group were associated with a variety of basic diseases with aggravated symptoms,which might be complicated by bacterial infection and myocardial injury.The incidence rate of chest distress and reduction rate of albumin in severe group were higher than those in normal group(P<0.01 and P<0.05).Conclusions:The COVID-19 is a rapid-developing and variable disease.During treatment,it is important to pay close attention to the development and changes of patients′chronic metabolic basic diseases and prevent the occurrence of bacterial infection and myocardial injury,which is of great significance to promote the patients′recovery.