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干扰素-α与白细胞介素-34检测在诊断狼疮性肾炎中的应用价值 被引量:1

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摘要 目的:探讨干扰素-α(IFN-α)与白细胞介素-34(IL-34)检测在诊断狼疮性肾炎(LN)中的应用价值。方法:选取2017年6月至2018年6月期间中国人民解放军联勤保障部队第九〇八医院肾内科收治的64例LN患者作为研究对象。对这64例患者均进行血清IFN-α和血清IL-34检测。然后,观察这些患者在不同活动期和不同病理分型期其血清IFN-α和血清IL-34的水平。结果:经检测,活动期的LN患者其血清IFN-α的水平和血清IL-34的水平均显著高于非活动期的LN患者,P<0.05;病理分型为Ⅳ期和为Ⅴ期的LN患者其血清IFN-α的水平和血清IL-34的水平均高于病理分型为Ⅱ期和为Ⅲ期的LN患者,且病理分型为Ⅴ期的LN患者其血清IFN-α的水平高于病理分型为Ⅳ期的LN患者,P<0.05。结论:血清IFN-α和血清IL-34检测在诊断LN中具有较高的应用价值。
出处 《当代医药论丛》 2020年第6期158-159,共2页
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