内镜下静脉曲张套扎术治疗老年肝硬化合并食管静脉曲张出血的效果及安全性

Efficacy and Safety of Endoscopic Variceal Ligation in the Treatment of Senile Cirrhosis with Esophageal Variceal Bleeding

目的:研究内镜下静脉曲张套扎术(EVL)治疗老年肝硬化合并食管静脉曲张出血的效果及安全性。方法:选择2016年1月-2019年1月笔者所在医院收治的老年肝硬化合并食管静脉曲张出血患者60例,使用抛掷硬币法分为EVL组和药物组,每组30例。EVL组使用EVL治疗,药物组使用醋酸奥曲肽和奥美拉唑治疗。对比两组治疗后临床疗效及不良反应情况。结果:EVL组总有效率为96.67%,高于药物组的73.33%,差异有统计学意义(P<0.05);EVL组不良反应发生率为3.33%,低于药物组的20.00%,差异有统计学意义(P<0.05)。结论:EVL治疗老年肝硬化合并食管静脉曲张出血的效果明显且安全性高。

Objective:To study the efficacy and safety of endoscopic variceal ligation (EVL) in the treatment of senile cirrhosis with esophageal variceal bleeding.Method:From January 2016 to January 2019,60 cases of senile cirrhosis with esophageal variceal bleeding were selected and treated in our hospital.The patients were divided into the EVL group and the drug group by coin toss method,with 30 cases in each group.The EVL group was treated with EVL,and the drug group was treated with Octreotide Acetate and Omeprazole.After treatment,the clinical efficacy and adverse reactions of the two groups were compared.Result:The total effective rate of the EVL group was 96.67%,which was higher than 73.33% of the drug group,and the difference was statistically significant (P<0.05).The incidence of adverse reactions in the EVL group was 3.33%,which was lower than 20.00% of the drug group,and the difference was statistically significant (P<0.05).Conclusion:EVL is effective and safe in the treatment of senile cirrhosis with esophageal variceal bleeding.