清热耳鸣方治疗神经性耳鸣(邪郁少阳痰瘀阻窍证)临床疗效及对血清5-羟色胺的影响

Efficacy of the Qingre Erming prescription on neurological tinnitus of the Xieyu Shaoyang Tanyu Zuqiao syndrome and 5-hydroxytryptamine

目的:评价清热耳鸣方治疗神经性耳鸣患者的临床疗效。方法:将60例神经性耳鸣(邪郁少阳痰瘀阻窍证)的患者随机分为对照组、观察组,各30例,观察患者总有效率、耳鸣致残量表(Tinnitus Handicap Inventory,THI)评分、抑郁自评量表(Self-rating Depression Scale,SDS)评分、焦虑自评量表(Self-rating Anxiety Scale,SAS)评分、血清5-羟色胺(5-Hydroxytryptamine,5-HT)水平变化。结果:两组治疗后总有效率差异有统计学意义,(P<0.05);治疗后两组THI评分、SDS评分、SAS评分、血清5-HT水平较治疗前均有明显改善(P<0.05),观察组更优(P<0.05)。结论:清热耳鸣方可明显提高神经性耳鸣患者的总有效率,改善患者耳鸣症状和心理状态。

Objective:To evaluate the clinical efficacy of the Qingre Erming prescription(清热耳鸣方)on neurological tinnitus of the Xieyu Shaoyang Tanyu Zuqiao syndrome(邪郁少阳痰瘀阻窍证).Methods:Sixty patients were randomly divided into the control group and the observation group,30 cases in each.The total efficiency,THI scale,SDS scale,SAS scale and serum 5-HT level were observed.Results:There was a significant difference in total efficiency between groups(P﹤0.05).After treatment,the THI score,SDS score,SAS score and serum 5-HT level in groups were improved in groups,and those in the observation group were significantly improved(P﹤0.05).Conclusion:The Qingre Erming prescription on nervous tinnitus shows good effects,can significantly improve the tinnitus symptoms and psychological state.