康复训练对脑梗死患者神经生化标志物水平及偏瘫肢体运动功能影响

Effect of rehabilitation training on the leves of neurobiochemical markers and hemiplegic motor function in patients with cerebral infarction

目的探讨康复训练对脑梗死患者神经生化标志物水平,以及偏瘫肢体运动功能的影响。方法选取2015年6月~2018年6月我院98例脑梗死患者随机分成两组,每组49例。对照组采用常规治疗方式,观察组在对照组基础上进行综合康复训练。观察比较两组患者的治疗效果、神经生化标志物水平、偏瘫肢体运动功能、神经功能缺损情况、日常生活能力情况。结果观察组患者的治疗总有效率为95.92%,对照组为71.43%,两组数据差异有统计学意义(P<0.05)。护理后,观察组患者的S100B神经生化标志物水平明显低于对照组,血清脑源性神经营养因子(BDNF)明显高于对照组,两组差异有统计学意义(P<0.05)。观察组患者的肢体运动功能评分(FMA)(80.56±7.75)分,明显高于对照组(70.85±7.89)分,两组差异有统计学意义(P<0.05)。观察组患者神经功能缺损评分(NIHSS)(9.63±2.75)分,明显低于对照组(13.57±3.49)分,两组差异有统计学意义(P<0.05)。护理后观察组患者的日常生活能力评分(Barthel)比对照组更高,差异有统计学意义(P<0.05)。结论康复训练有利于改善脑梗死患者的神经生化标志物水平,提高偏瘫肢体运动功能,改善患者的神经功能缺损情况和日常生活能力。

Objective To explore the effect of rehabilitation training on the levels of neurobiochemical markers in patients with cerebral infarction and the motor function of hemiplegia.Methods From June 2015 to June 2018,98 patients with cerebral infarction in our hospital were randomly divided into two groups,with 49 cases in each group.The control group was treated with conventional treatment,and the observation group was given comprehensive rehabilitation training based on the treatment of the control group.The therapeutic effect,neurobiochemical markers,hemiplegia motor function,neurological deficits,and daily living ability were compared between the two groups.Results The total effective rate of the observation group was 95.92%,which was significantly higher than that of the control group(71.43%),and the difference was statistically significant(P<0.05).The level of S100 B neurobiochemical markers in the observation group was significantly lower than that in the control group after nursing.And serum brain-derived neurotrophic factor(BDNF)in the observation group was significantly higher than that of the control group,and the difference was statistically significant(P<0.05).The limb motor function score(FMA)of the observation group was(80.56±7.75)points,which was significantly higher than that in the control group[(70.85±7.89)points],and the difference was statistically significant(P<0.05).The neurological deficit score(NIHSS)of the observation group was(9.63±2.75)points,which was significantly lower than that in the control group[(13.57±3.49)points],and the difference was statistically significant(P<0.05).The postoperative daily life ability score(Barthel)of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Rehabilitation training is beneficial to improve the level of neurobiochemical markers,improve the motor function of hemiplegia,and improve the neurological deficit and daily living ability in patients with cerebral infarction.