8876例不同性别患者尖锐湿疣组织HPV基因型对比研究

Comparison of HPV genotype in different gender among 8876 patients with condyloma acuminatum

目的:分析男性和女性尖锐湿疣患者HPV基因型分布特点。方法:回顾性分析2010年9月至2019年9月我院确诊的8876例CA患者(男5717例,女3159例)HPV基因型。结果:男女患者均以20~29岁最多。女性多重感染率为47.07%,高于男性的36.85%,差异具有统计学意义(χ^2=88.144,P<0.0001)。女性高危型的感染率为46.35%,高于男性的34.60%,差异具有统计学意义(χ^2=120.069,P<0.0001)。结论:男性和女性CA患者HPV基因型分布特点不同,女性多重感染率和高危型HPV感染率显著高于男性。

Objective:To analyze the difference in HPV genotype between male and female.Methods:The data of 8876 patients(5717 males and 3159 females)with Condyloma acuminatum(CA)diagnosed from September 2010 to September 2019 was analyzed retrospectively.Results:Of 8876 patients,the age was from 20 to 29 years old in majority of the patients.The rates of multiple infection were 47.07%in females and 36.85%in males,with a significant difference(χ^2=88.144,P<0.0001).The rate of high-risk type infection was 46.35%in females and 34.60%in males,with a significant difference(χ^2=120.069,P<0.0001).Conclusion:The HPV genotype was different between males and females.The infection rates of multiple infection and high-risk type in females were higher than in males.