更深度的“照相”技术——质谱成像的发展与应用

More in-Depth “Photography” Technology:The Development and Application of Mass Spectrometry Imaging

质谱成像是质谱技术在发展过程中所衍生出的前沿性科研领域,是一种将质谱技术和影像可视化技术结合而成的高科技"拍照"手段。它可以在没有特异性标记的情况下,对小分子、多肽、蛋白质等目标分子进行分析,在利用质谱分析提供目标化合物的结构信息的同时,提供其空间分布和含量变化信息。该技术在生物医药、临床医学、病理学、生命科学研究等领域具有极大的应用前景。

Mass spectrometry imaging is a frontier research field derived from the development of mass spectrometry. It is the combination of mass spectrometry and imaging techniques, which can get the molecular structure information and the spatial distribution information at the same time without labeling. Mass spectrometry imaging has tremendous applications in the fields of biomedicine, clinical medicine, pathology and life science research for the analyzing of small molecules, peptides, metabolites, etc.