左归丸联合体外冲击波治疗轻中度膝骨关节炎肝肾阴虚证的临床观察

目的观察左归丸联合体外冲击波治疗轻中度膝骨关节炎肝肾阴虚证的临床疗效.方法选取2016年9月至2017年9月于本院门诊就诊的90例轻中度膝骨关节炎肝肾阴虚证的患者,其中治疗组45例,对照组45例.治疗组给予体外冲击波疗法和左归丸加减口服治疗,对照组采用口服塞来昔布胶囊治疗,两组均治疗12周.结果83例患者获得12周的随访,其中治疗组43例,对照组40例.两组治疗结束后在各项评分上较治疗前均有明显改善,差异具有统计学意义(P<0.05);治疗结束后,两组在各项评分上比较,治疗组均优于对照组,差异具有统计学意义(P<0.05).结论左归丸联合体外冲击波治疗轻中度膝骨关节炎肝肾阴虚证的疗效较好,值得临床推广.

Objective To observe the clinical effect of Zuogui pill combined with extracorporeal shock wave in the treatment of mild to moderate knee osteoarthritis,with the liver and kidney yin deficiency.Methods From September 2016 to September 2017,90 patients with liver and kidney yin deficiency syndrome of mild to moderate knee osteoarthritis were selected from the outpatient department of our hospital,including 45 in the treatment group and 45 in the control group-the treatment group was treated with extracorporeal shock wave therapy and Zuogui pill,while the control group was treated with celecoxib capsule,both groups were treated for 12 weeks.Results 83 patients were followed up for 12 weeks,43 in the treatment group and 40 in the control group.After treatment,the scores of the two groups were significantly improved compared with those before treatment,the difference is statistically significant(P<0.05).After treatment,the scores of the treatment group were better than the control group,with statistical significance(P<0.05).Conclusion Zuogui pill combined with extracorporeal shock wave is effective in the treatment of liver and kidney yin deficiency of mild to moderate knee osteoarthritis,and it is worthy of clinical application.