基于瘀热理论探讨放射性损伤的病因病机及防治原则

Discussion on Preventive and Therapeutic Principle of Radiation Injury Based on the Theory of Stasis and Heat

随着核医学的发展,放射治疗在肿瘤的综合治疗中占有重要的地位,但放射性损伤是限制其发展的主要瓶颈。以国医大师周仲瑛教授的瘀热病机理论为指导,认为放射性损伤的中医病因病机为瘀热相搏、气阴两伤,放射性损伤有灼伤性、迟发性、损络性、伤阴性、耗气性等致病特点,中医对放射性损伤的诊断一般区分为头颈部、胸部、上腹部、下腹部四个部位,根据所损伤的脏腑、组织、器官的不同,而有不同的临床表现,提出凉血化瘀、养阴益气的防治原则。

Along with the development of nuclear medicine,radiation therapy is very important in the comprehensive treatment of tumor,but radiation damage is the main bottleneck restricting its development.National traditional Chinese medicine(TCM)master Professor Zhou Zhongying held that the etiology and pathogenesis of radiation injury was fighting of static blood and extreme heat,as well as deficiency of qi and yin under the guidance of the theory of stasis and heat.Radiation injury was characterized by burning pain,delayed traumatic,damaged collateral,impaired yin and qi.In TCM,the focus of it is usually classified by its location in head and neck,chest,epigastrium and hypogastrium.When it came to different foci,the clinical manifestation would be different.Hence,Professor Zhou regarded cooling blood and dispersing stasis along with nourishing yin and invigorating qi as its preventive and therapeutic principle.