血白蛋白水平对缺血性肠病预后的预测价值

Predictive Value of Serum Albumin Level in the Prognosis of Patients with Ischemic Bowel Disease

目的分析血白蛋白(ALB)水平预测缺血性肠病(ICBD)预后的价值。方法将268例缺血性肠病患者根据是否发生院内死亡分为死亡组(33例)和生存组(235例)。采用单因素和多因素logistic回归分析ICBD预后的影响因素,并运用ROC曲线分析ALB与其他血液学指标预测ICBD预后的价值。结果纳入的268例患者发生院内死亡的占12.3%。多因素logistic回归分析显示,血ALB水平是ICBD患者发生院内死亡的保护性因素(OR:0.817,95%CI:0.714~0.935,P=0.003)。ALB预测ICBD预后的ROC曲线下面积为0.833,最佳截断值为34 g·L-1,敏感度为87.88%,特异度为61.70%,较其他血液学指标预测价值高。结论 ALB是ICBD患者预后的保护性因素,早期检测患者血ALB水平对预后的预测有重要意义。

Objective To analysis of the value of serum albumin(ALB) levels in predicting the prognosis of ischemic bowel disease(ICBD).Methods A total of 268 patients with ischemic bowel disease were divided into death group(33 cases) and survival group(235 cases) according to whether in-hospital death occurred. The influencing factors of ICBD prognosis were analyzed by univariate and multivariate logistic regression. ALB with other hematological indicators predicting the value of ICBD prognosis was used by ROB curve.Results The inclusion of 268 patients accounted for 12.3% of in-hospital deaths. Multivariate logistic regression showed that blood ALB levels was a protective factor for in-hospital death in patients with ICBD(OR: 0.817, 95% CI: 0.714-0.935, P=0.003). ALB predicted the prognosis of ICBD with an area under the ROC curve of 0.833, an optimal cut-off value of 34 g·L-1, a sensitivity of 87.88%, and a specificity of 61.70%, which were higher than other hematological indicators.Conclusion ALB is a protective factor for the prognosis of patients with ICBD, and early detection of blood ALB levels is important for prognosis prediction.