CDFI血流分级联合收缩期与舒张末期流速比值鉴别卵巢良恶性肿瘤的临床价值

Clinical value of CDFI blood flow grade and systolic to end diastolic velocity ratio in differential diagnosis of benign and malignant ovarian tumors

目的探讨CDFI血流分级和收缩期与舒张末期流速比值(S/D)在鉴别卵巢良恶性肿瘤中的临床价值。方法选取我院确诊的卵巢癌患者96例(病例组)和同期卵巢良性病变患者96例(对照组),均行CDFI检查卵巢并测定血流分级、S/D值。以病理学检查为标准,绘制受试者工作特征(ROC)曲线评估血流分级、S/D值及二者联合应用时鉴别卵巢良恶性肿瘤的效能。结果病例组血流分级、S/D值均明显高于对照组,差异均有统计学意义(均P<0.05)。以血流分级Ⅱ级为截断值,其鉴别卵巢良恶性肿瘤的敏感性、特异性、准确率分别为81.25%、83.33%、82.29%;以S/D值2.20为截断值,其鉴别卵巢良恶性肿瘤的敏感性、特异性、准确率分别为87.50%、81.25%、84.38%;两者联合应用时诊断敏感性、特异性、准确率分别为95.83%、93.75%、94.79%,明显高于单独应用,差异均有统计学意义(均P<0.05)。结论CDFI血流分级及ROC曲线评价S/D值对鉴别卵巢良恶性肿瘤的效能良好,二者联合应用可提高诊断准确率。

Objective To explore the clinical value of CDFI blood flow grade and systolic to end-diastolic velocity ratio(S/D)in differential diagnosis of benign and malignant ovarian tumors.Methods A total of 96 patients with ovarian cancer(case group)and 96 patients with benign ovarian disease(control group)diagnosed in our hospital were selected,the blood flow grade and S/D value were determined by CDFI.Based on the pathological examination,the receiver operating characteristic(ROC)curve was drawn to evaluate the blood flow grading and the S/D value and the effectiveness of the two parameters in differentiating benign and malignant ovarian tumors.Results The blood flow grade and S/D values of case group were significantly higher than those of control group,and the differences were statistically significant(both P<0.05).The sensitivity,specificity and accuracy of the differentiation of the benign and malignant ovarian tumors were 81.25%,83.33%and 82.29%when the blood flow grade was≥Ⅱ.The sensitivity,specificity and accuracy of the differentiation of the benign and malignant ovarian tumors were 87.50%,81.25%and 84.38% when the S/D value≥2.20,When the two were combined,the sensitivity,specificity and accuracy of differentiation of ovarian benign and malignant tumors were 95.83%,93.75%and 94.79%,respectively,which were significantly higher than those of the single application,and the differences were statistically significant(all P<0.05).Conclusion CDFI blood flow grade and S/D value have good diagnostic efficacy in differentiating benign and malignant ovarian tumors,and their combined application can further improve the diagnostic accuracy.