新辅助化疗联合TNBC手术切除治疗三阴性乳腺癌的效果

Effect of Neoadjuvant Chemotherapy combined with TNBC Resection for triple negative Breast Cancer

目的探讨新辅助化疗联合TNBC手术切除对三阴性乳腺癌的治疗效果。方法对安阳市肿瘤医院2015年10月-2017年10月间收治的72例三阴性乳腺癌患者进行研究,根据治疗方法不同分为对照组和观察组。对照组接受TNBC手术,观察组与新辅助化疗联合使用,进行两组疾病治疗成效的对比。结果观察组疾病缓解率为52.8%,并发症发生率为11.1%,与对照组的27.8%和33.3%相比,存在显著差异(P<0.05);对照组和观察组两组患者治疗前的生活质量对比无显著差异(P>0.05),观察组治疗后生活质量评分明显高于对照组(P<0.05)。结论新辅助化疗联合TNBC手术治疗可促进三阴性乳腺癌缓解率和患者生活质量的提升,也可进行并发症的防范,应用价值高。

Objective To evaluate the effect of neoadjuvant chemotherapy combined with TNBC in the treatment of triple negative breast cancer. Methods A total of 72 patients with triple negative breast cancer admitted to Anyang Cancer Hospital from October 2015 to October 2017 were studied. Control Group received TNBC surgery, Observation Group and neoadjuvant chemotherapy in combination, the two groups of disease treatment results were compared. Results The remission rate and complication rate were 52.8% and 11.1% in the observation group, compared with 27.8% and 33.3% in the control group(P < 0.05) There was no significant difference in the quality of life before treatment between the two groups(P > 0.05), and the score of the quality of life in the observation group was significantly higher than that in the control group(P < 0.05). Conclusion Neoadjuvant chemotherapy combined with TNBC can improve the remission rate and quality of life of patients with triple negative breast cancer.