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痛风性关节炎患者第一跖趾关节尿酸盐沉积与血清尿酸水平的关系研究 被引量:14

On the Relationship Between the Deposition of Urate in the First Metatarsopha-langeal Joint and Serum Uric Acid Level in Patients with Gouty Arthritis
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摘要 目的:分析痛风性关节炎患者第一跖趾关节尿酸盐沉积与血清尿酸的关系。方法:对66例痛风性关节炎患者患侧第一跖趾关节进行高频超声检查,观察关节腔内有无尿酸盐沉积、"双轨征"及痛风石形成,记录血清尿酸是否增高,并在组间进行统计学分析。结果:66例患者中,关节腔内尿酸盐沉积、"双轨征"以及痛风石形成者阳性率分别为86.36%、53.03%、33.33%。39例血清尿酸高于正常值,27例血清尿酸低于正常值。血清尿酸增高组与尿酸正常组软组织尿酸盐沉积检出率分别为82.05%(32/39)和92.59%(25/27),差异无统计学意义(χ^2=0.74,P>0.05);血清尿酸增高组与尿酸正常组间软骨表面双轨征检出率分别为43.59%(17/39)和66.67%(18/27),差异无统计学意义(χ^2=3.41,P>0.05);血清尿酸增高组与尿酸正常组间关节腔内痛风石形成检出率分别为25.64%(10/39)和44.44%(12/27),差异无统计学意义(χ^2=1.76,P>0.05)。结论:血清尿酸不能直接反映尿酸在人体组织内的沉积情况,因而在血清尿酸检查呈阴性时,仍需进行超声检查,以明确痛风性关节炎的诊断。
作者 付卓 沈素红 耿丰勤 陈超 张要丽 FU Zhuo;SHEN Su-hong;GENG Feng-qin;CHEN Chao;ZHANG Yao-li
出处 《风湿病与关节炎》 2020年第5期32-34,共3页 Rheumatism and Arthritis
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