肺腺癌临床病理特征与淋巴结转移关系

Relationship between clinicopathological features and lymph node metastasis of lung adenocarcinoma

①目的探讨肺腺癌临床病理特征与淋巴结转移的关系。②方法收集华北理工大学附属医院胸外科经手术切除+系统淋巴结清扫或采样患者101例,回顾患者一般临床资料及病理资料,如性别、年龄、吸烟史、术前胸部X线影像、是否侵犯周围组织以及淋巴结转移状态等,进行卡方检验及多因素Logistic分析。③结果 101例患者有29例出现淋巴结转移(28.7%),Fisher精确检验提示,肿瘤直径、癌组织病理类型及肿瘤侵犯邻近组织与淋巴结转移有关(P<0.05);多因素Logistic回归分析提示,肿瘤侵犯邻近组织是淋巴结转移的独立危险因素(P<0.05)。④结论肺腺癌肿瘤直径、病理类型及肿瘤侵犯邻近组织可能是淋巴结转移的预测因子。

Objective To explore the relationship between clinicopathological features and lymph node metastasis of lung adenocarcinoma.Methods A total of 101 patients undergoing surgical resection and systemic lymph node dissection or sampling were collected from the Department of Thoracic Surgery, North China University of Science and Technology.The general clinical pathological data such as gender,age,smoking history,preoperative chest imaging,surrounding tissue invasion and lymph node metastasis were reviewed. State, etc., chi-square test and Logistic multi-factor analysis.Results Lymph node metastasis occurred in 29 patients(28.7%). Fisher’s exact test showed that tumor diameter,pathological type of cancer and the tumor invaded adjacent tissues were associated with lymph node metastasis(P<0.05). Logistic multivariate analysis suggested that the tumor invaded adjacent tissues was independent risk factors for lymph node metastasis(P<0.05).Conclusion Tumor diameter,pathological type and the tumor invaded adjacent tissues in lung adenocarcinoma may be predictors of lymph node metastasis.