期刊文献+

人体衰老评估方法的研究进展 被引量:4

Progress on assessment methods for aging
下载PDF
导出
摘要 随着人口老龄化加快,与衰老相关疾病的经济负担不断加重,有关衰老问题的研究受到了前所未有的重视。然而,现有衰老评估的研究虽从分子生物学、临床医学、流行病学等方面取得了不少成果,但由于评估形式繁杂、内容多样、标准各异、缺乏敏感的生物学标志物等问题,仍面临很多困难。为此,本文概述了衰老评估方法以及目前衰老评估常用和新兴生物标志物的研究进展。 With the acceleration of population aging and the increasing economic burden of aging related diseases,the research on aging has received unprecedented attention.However,although many achievements have been made in molecular biology,clinical medicine and epidemiology,there are still many difficulties in aging assessment due to the complex forms,various contents,different standards and lack of sensitive biological markers.Therefore,in this paper,we summarize the methods of aging assessment and the research progress of common and emerging biomarkers in the assessment.
作者 高伟健 王征旭 GAO Wei-Jian;WANG Zheng-Xu(Graduate School of Chinese PLA General Hospital, Beijing 100853, China;Biotherapy Center, Seventh Medical Center, Chinese PLA General Hospital, Beijing 100700, China)
出处 《中华老年多器官疾病杂志》 2020年第5期393-396,共4页 Chinese Journal of Multiple Organ Diseases in the Elderly
关键词 衰老 衰弱指数 评估 生物标志物 aging frailty index evaluation biomarkers
  • 相关文献

参考文献2

二级参考文献32

  • 1顾大男,曾毅,柳玉芝,曾宪新.中国老年人虚弱指数及其与痛苦死亡的关系研究[J].人口研究,2007,31(5):35-41. 被引量:36
  • 2KINSELL K, HE Wu. An aging world: 2008 [ R]. US Census Bureau International Population Reports, 2009 : 95.
  • 3FERRUCCI L, GURALNIK J M, CAVAZZINI C, et al. The frailty syndrome: a critical issue in geriatric ontology [ J]. Critical Reviews in Oncology/Hematology, 2003, 46 (2) : 127 - 137.
  • 4FISHER A L. Just what defines frailty? [J]. Journal of the American Geriatrics Society, 2005, 53 (12) : 2229 -2230.
  • 5FRIED L P, FERRUCCI L, DARER J, et al. Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care [ J]. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2004, 59 (3) : M255 -M263.
  • 6KULMINSKI A, YASHIN A, UKRAINTSEVA S, et al. Accumulation of health disorders as a systemic measure of aging: findings from the NLTCS data [J]. Mechanisms of Ageing and Development, 2006, 127 (11) : 840 -848.
  • 7ROCKWOOS K, MITNITSKI A. Frailty in relation to the accumulation of deficits [J].The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, 2007, 62 (7) : 722 -727.
  • 8ROMERO R, KENNY R A. The frailty index in Europeans: association with age and mortality [J]. Age and Ageing, 2012 (1) : 1 -6.
  • 9GARCIA J J, GARCIA-PENA C, FRANCO-MARINA F, et al. A frailty index to predict the mortality risk in a population of senior Mexican adults [J]. BMC Geriatrics, 2009, 9 (1): 47-55.
  • 10SEARLE S D, MITNITSKI A, GAHBAUER E A, et al. A standard procedure for creating a frailty index [J]. BMC Geriatrics, 2008, 8 (1) : 24 -34.

共引文献17

同被引文献43

引证文献4

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部