鞘内药物输注设备治疗癌痛的适应证及注意事项

Indications and Precautions of Intrathecal Drug Infusion Devices for the Treatment of Cancer Pain

癌症是威胁人类生命的难治性疾病之一。晚期癌症常伴随出现疼痛,称之为癌痛,是困扰和降低晚期癌症患者生活质量的一大问题。随着人类对蛛网膜下腔药物扩散研究的深入,鞘内注射(IT)给药方式逐渐应用到疾病的治疗当中。其中鞘内药物输注设备(IDD)被大量应用于临床。本文回顾了近年文献,涉及IDD适应证及临床效果、禁忌证及注意事项和经济学因素,对IDD应用于癌痛的现状进行了总结,得出在IDD使用时需权衡利弊,尊重患者意愿,并尽可能降低成本的结论。

Cancer is one of the refractory diseases threatening human life.Advanced cancer is often accompanied by pain,known as cancer pain,which is a major problem that afflicts and reduces the quality of life of such patients.With the deepening of the research on subarachnoid drug diffusion,intrathecal infusion has been applied to the treatment of this disease.Among them,IT drug delivery(IDD)devices are widely used in clinical practice.On the basis of reviewing the recent studies on the indications,clinical effects,contraindications,precautions and economic factors,we summarized the application status of IDD devices in cancer pain,and concluded that when using IDD devices,it is necessary to weigh the advantages and disadvantages,respect patients'intention,and reduce the cost as much as possible.