摘要
埃博拉病毒具有高度传染性,可引起严重出血热的暴发,致死率高达90%。目前没有疫苗、生物制剂或特异性的小分子化合物类防治药物。近几年,大量文献报道了埃博拉病毒抑制剂,本文综述了该领域的研究新进展。
Ebola virus is extremely virulent and highly contagious.Ebola virus causes outbreaks of severe hemorrhagic fever,with human mortality rates of up to 90%.There is currently no preventive or therapeutic treatment in the form of vaccines,biological or small molecular agents.Currently,a lot of anti-Ebola virus agents have been reported.Here,we review the latest advances in this field.
作者
任玉洁
张硕
魏粉菊
刘新泳
展鹏
REN Yu-jie;ZHANG Shuo;WEI Fen-ju;LIU Xin-yong;ZHAN Peng(Department of Medicinal Chemistry,Key Laboratory of Chemical Biology(Ministry of Education),School of Pharmaceutical Sciences,Shandong University,Jinan 250012,China)
出处
《药学学报》
CAS
CSCD
北大核心
2020年第4期694-702,共9页
Acta Pharmaceutica Sinica
基金
国家自然科学基金重点国际合作研究项目(81420108027)
山东省重点研发计划(2017CXGC1401,2019JZZY021011)。
