放疗及其时机对组织扩张器-假体植入乳房重建的影响及研究进展

Research progress in the effect of radiotherapy and its timing on tissue expander/prosthesis implantation-based breast reconstruction

随着放疗在乳腺癌治疗中的适应证不断扩大,越来越多的患者在乳房切除术后需要放疗,而伴随着乳房重建的开展,在治疗肿瘤获益的同时,放疗及其时机的选择又会给乳房重建带来影响,可能导致术后并发症和美容效果迥异。如何优化乳腺癌术后乳房重建与放疗等综合治疗的策略,尤其是乳房重建的技术和放疗时机选择等,已成为放疗科、乳腺外科和整形外科等多学科治疗共同关注的问题。本文旨在回顾和汇总该领域最新的高质量研究,从放疗及其时机选择对组织扩张器/假体乳房重建的影响、假体重建率及术后患者满意度等方面进行综述,以便学者了解与放疗和乳房重建相关的最新研究进展,帮助临床医师优化治疗方案。

As indications of radiotherapy in the treatment of breast cancer continue to expand,more and more patients need radiotherapy after mastectomy.With the development of breast reconstruction,radiotherapy and its timing will affect breast reconstruction while patients benefit from tumor treatment and may lead to different postoperative complications and cosmetic effects.How to optimize the comprehensive therapeutic strategies of postoperative breast reconstruction and radiotherapy for breast cancer,especially the techniques of breast reconstruction and the choices of radiotherapy timing,has become an issue of common concerns of multidisciplinary treatment involving radiotherapy,breast surgery,and plastic surgery.This paper aims to review and summarize the latest high-quality research in this field including the impact of radiotherapy and its timing on tissue expander/prosthetic breast reconstruction,rate of prosthetic reconstruction,and postoperative patient satisfaction so that scholars can understand the latest research progress of radiotherapy and breast reconstruction and clinicians can optimize therapeutic regimens.