导管相关的血液感染及病原学分析

Etiological Analysis of Catheter-Related Blood Infection

目的分析导管相关性血液感染的病原学分布特点,探讨实施综合防控措施管理的干预效果。方法将2017年2月至8月温州医科大学附属第二医院重症监护科(intensive care unit,ICU)留置中心静脉导管的239例患者作为常规组,对其临床资料进行回顾性分析,统计导管相关性血液感染的发生率及病原学分布特点,制定相应的综合防控措施;将2018年2月至8月ICU收治的留置中心静脉导管的239例患者作为干预组,实施综合防控措施管理。比较两组患者导管相关性血液感染的发生率及导管病原体检出数。结果干预组导管相关性血液感染的发生率3.35%(8/239)明显低于常规组的8.79%(21/239),病原体检出数10株明显低于常规组的24株,差异具有统计学意义(p<0.05)。结论通过对ICU留置中心静脉导管患者实施综合防控措施管理,有效降低了导管相关性血液感染发生率及导管病原体检出数。

Objective To analyze the etiological characteristics of catheter-related bloodstream infections,and to explore the effect of comprehensive prevention and control management.Methods A total of 239 patients with central venous catheter in intensive care unit(ICU)of the Second Affiliated Hospital of Wenzhou Medical University from February to August 2017 were included into the routine group.Their clinical data were retrospectively analyzed to explore the incidence of catheter-related bloodstream infections and etiological characteristics.Comprehensive prevention and control measures were developed.And 239 patients with central venous catheters in the ICU from February to August 2018 were taken as the intervention group,and they were managed with comprehensive prevention and control management.The incidence of catheter-related bloodstream infections and the number of catheter pathogens detected in the two groups were compared.Results The incidence of catheter-related bloodstream infection in the intervention group was 3.35%(8/239),which was significantly lower than that in the conventional group,8.79%(21/239)(p<0.05).The number of pathogens detected in the observation group(10)was significantly lower than that in the conventional group(24)(p<0.05).Conclusion The implementation of comprehensive prevention and control measures for patients with central venous catheters in ICU effectively reduced the incidence of catheter-related bloodstream infections and the number of pathogens detected.