摘要
长期饮酒可导致认知损害,但具体机制尚不明确.血浆同型半胱氨酸水平升高与酒依赖所致认知损害密切相关,现从同型半胱氨酸的生物效应、与酒精相关认知损害的关系及治疗进展等几方面对同型半胱氨酸与酒依赖所致认知损害的研究加以综述.
Chronic alcohol consumption can induce cognitive impairment,whereby the exact mechanism remains unknown.Elevated plasma homocysteine level are closely related to cognitive impairment in alcohol-dependent patients.This article reviews the research of homocysteine and cognitive impairment in alcohol dependent patients,from the aspects of biological effects of homocysteine,the relationship between homocysteine and alcohol-related cognitive impairment,and treatment progress.
作者
徐琳
王学义
Xu Lin;Wang Xueyi(Department of Psychiatry,the First Hospital of Hebei Medical University,Menial Health Institute of Hebei Medical University,Brain Aging and Cognitive Neuroscience Laboratory,Shijiazhuang 050031,China)
出处
《神经疾病与精神卫生》
2019年第12期1084-1088,共5页
Journal of Neuroscience and Mental Health
关键词
酒依赖
认知损害
同型半胱氨酸
多态性
单核苷酸
综述
Alcohol dependence
Cognitive impairment
Homocysteine
Polymorphism
single nucleotide
Review
