微RNA在下颌髁突软骨生长发育中作用的研究进展

Advances in research of microRNA in the growth and development of mandibular condyle cartilage

微RNA(micro RNA,miRNA)是一类小的非编码单链RNA,通过与信使RNA结合发挥其生物学作用。研究显示miRNA可能在调节下颌髁突软骨的生长发育中起重要作用。本文就miRNA的产生及其作用机制,对下颌髁突软骨生长发育相关的miRNA研究进展进行综述,以期助于进一步研究下颌髁突软骨生长发育。

MicroRNA(miRNA)are a class of small non-coding single-stranded RNA that exert their biological effects by binding to target messenger RNA(mRNA).There is new evidence that miRNA may play an important role in regulating the growth and development of mandibular condylar cartilage.In this paper,the production and mechanism of miRNA are reviewed,and the progress of studies on the growth and development of mandibular condylar cartilage,which is helpful to further study the growth and development of mandibular condylar cartilage.