绒毛膜羊膜炎与产后母婴发生临床感染的关系

Relationship between chorioamnionitis and clinical infection of postpartum mother and infant

目的探讨绒毛膜羊膜炎与产后母体和新生儿发生临床感染性疾病的关系。方法回顾性分析1973例2018年在某中心产科分娩且进行了胎盘病理检查的产妇及新生儿感染发生情况的相关资料,根据胎盘病检是否存在绒毛膜羊膜炎进行分组,分析绒毛膜羊膜炎与产后母体、新生儿发生临床感染之间的关系。结果符合研究的1973例产妇中,组织学绒毛膜羊膜炎发生率为43.84%,观察1组中产后母体感染比例明显高于对照1组,两组数据差异有统计学意义(χ^2=14.534,P=0.000,OR=4.156)。符合研究条件的新生儿病例中,组织学绒毛膜羊膜炎占42.83%;观察2组与对照2组研究对象的胎龄、体重、性别相比,差异均无统计学意义(P>0.05),两组数据比较,观察2组中新生儿出现临床感染比例明显高于对照2组,差异有统计学意义(χ^2=30.299,P=0.000,OR=2.133);分娩方式不同,组织学绒毛膜羊膜炎的新生儿发生临床感染的差异无统计学意义(P>0.05)。结论组织学绒毛膜羊膜炎的产妇,产后感染风险明显增加,新生儿出现临床感染的风险明显增加,组织学诊断为绒毛膜羊膜炎的新生儿出现临床感染与分娩方式无关。

Objective To investigate the relationship between chorioamnionitis and postpartum maternal and neonatal clinical infections.Methods A retrospective analysis of 1973 cases of maternal and neonatal infections in the Department of Obstetrics and Gynecology in Huizhou Maternal and Child Health Care and Family Planning Service Center in 2018,and the occurrence of placental pathological examination,according to the presence of chorioamnionitis Grouped to analyze the relationship between chorioamnionitis and postpartum maternal and neonatal clinical infections.Results Among the 1973 women who met the study,the incidence of histological chorioamnionitis was 43.84%.The proportion of maternal infection in the observation 1 group was significantly higher than that of the control 1 group.The difference between the two groups was statistically significant(χ^2=14.534,P=0.000,OR=4.156).The histological chorioamnionitis accounted for 42.83%of the neonates who met the study conditions.There was no difference in the gestational age,body weight and sex between the observation 2 group and the control 2 group(P>0.05),the comparison of the two groups of data,the proportion of neonatal infection in the observation 2 group was significantly higher than the control 2 group,the difference was statistically significant(χ^2=30.299,P=0.000,OR=2.133);different modes of delivery,There was no significant difference in incidence of clinical infection in the neonates with histological chorioamnionitis(P>0.05).Conclusion The risk of postpartum infection is significantly increased in the mother with histological chorioamnionitis,and so do the neonates.But the clinical infection of neonates with histological chorioamnionitis is not related to the mode of delivery.