黄岐地区成人血脂异常与胃息肉的相关性研究

Correlation between abnormal lipids and gastric polyps in adults in Huangqi region

目的探讨黄岐地区成人血脂异常和胃息肉相关性。方法选取2019年2月~2019年11月某院经胃镜诊断为胃息肉患者100例作为试验组,选取同期经胃镜检查诊断为非萎缩性胃炎100例作为对照组,根据试验组患者病理类型分为增生性(52例)、腺瘤性(21例)、炎性(27例),根据试验组患者息肉部位分为胃体(54例)、胃底(17例)、胃窦(29例),比较各组患者总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白a、载脂蛋白b、癌胚抗原(CEA),分析血脂异常和胃息肉发生相关性。结果试验组患者TC、TG、载脂蛋白a、载脂蛋白b水平显著高于对照组,试验组患者HDL-C水平低于对照组患者(P<0.05)。试验组增生性、腺瘤性、炎性病理类型息肉患者TC、TG、HDL-C、LDL-C、载脂蛋白a、载脂蛋白b、CEA水平比较差异无统计学意义(P>0.05);试验组胃体、胃底、胃窦部位息肉患者TC、TG、HDL-C、LDL-C、载脂蛋白a、载脂蛋白b、CEA水平比较差异无统计学意义(P>0.05)。Spearman分析得出,TC、TG、载脂蛋白a、载脂蛋白b与胃息肉发生均呈正相关性,HDL-C与胃息肉发生呈负相关性。结论黄岐地区成人血脂发生和胃息肉呈密切相关性。

Objective To investigate the correlation between dyslipidemia and gastric polyps in adults in Huangqi area.Methods Select 100 case of gastric polyps patients in our hospital during Feb.2019~Nov.2019 as experimental group,100 cases of non-atrophic gastritis diagnosed by gastroscopy during the same period were selected as the control group.According to the pathological type of patients in the experimental group,they were divided into proliferative(52 cases),adenoma(21 cases),and inflammatory(27 cases).According to the location of patients’gastric polyp in the experimental group,the polyps were divided into gastric corpus(54 cases),fundus(17 cases)and Gastric antrum(29 cases).Compare patients in each group with total cholesterol(TC),triglycerides(TG),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C),apolipoprotein a,apolipoprotein b,cancer Embryonic antigen(CEA)to analyze the association between dyslipidemia and occurrence of gastric polyps.Results The levels of TC,TG,apolipoprotein a,and apolipoprotein b in the experimental group were significantly higher than those in the control group,and the HDL-C levels in the experimental group was lower than that in the control group(P<0.05).There was no statistically significant difference in patients with proliferative,adenomatic,or inflammatory pathological polyps in the experimental group on the levels of TC,TG,HDL-C,LDL-C,apolipoprotein a,apolipoprotein b,and CEA(P>0.05);The levels of TC,TG,HDL-C,LDL-C,apolipoprotein a,apolipoprotein b,and CEA in patients with gastric body,gastric fundus,and gastric antrum polyps were not statistically significant in the experimental group(P>0.05).Spearman analysis showed that TC,TG,apolipoprotein a,apolipoprotein b were positively correlated with the occurrence of gastric polyps,and HDL-C was negatively correlated with the occurrence of gastric polyps.Conclusion The occurrence of blood lipids in adults in Huangqi area was closely related to gastric polyps.