综合性康复干预对稳定期双相情感障碍患者情绪和社会功能的影响

Effect of comprehensive rehabilitation intervention on emotional and social function of patients with stable bipolar disorder

目的探讨综合性康复干预对稳定期双相情感障碍(BAD)患者情绪和社会功能的影响。方法选取2015年1月~2017年12月精神科就诊的稳定期BAD患者共90例,随机分为干预组和对照组各45例。对照组予以常规康复干预,干预组在对照组治疗基础上予以综合性康复干预。两组患者干预均8周。观察并评估两组患者治疗后的临床效果,并比较两组患者干预前后情绪和社会功能的变化,随访1年比较其复发率。结果干预8周后,干预组患者的临床总有效率(95.56%)明显高于对照组(82.22%)(χ^2 =4.05,P<0.05);同时两组患者YMRS评分、SDS评分和SDSS评分均较干预前明显下降(P<0.05或P<0.01),且干预组患者下降幅度较对照组更显著(P<0.05)。随访1年,干预组和对照组患者病情复发率分别为17.78%(8/45)和37.78%(17/45),干预组患者的病情复发率明显低于对照组(χ^2 =4.49,P<0.05)。结论综合性康复干预用于稳定期BAD患者的效果较确切,能明显改善躁狂和抑郁症状,调节患者的情绪,促进社会功能的恢复,能降低其病情复发率。

Objective To investigate the effects of comprehensive rehabilitation intervention on emotional and social function in the patients with stable bipolar disorder(BAD).Methods A total of 90 patients with stable BAD from January 2015 to December 2017 who were admitted to the Department of Psychiatry were selected and were randomly divided into the intervention group and the control group,with 45 patients in each group.The patients in the control group were given routine rehabilitation intervention on this basis.The patients in the intervention group were given comprehensive rehabilitation intervention on the basis of the control group.Both groups of patients were treated for 8 weeks.The clinical effects of the two groups of patients after treatment were observed and evaluated,and the changes in emotional and social function were compared between the two groups before and after intervention.The recurrence rate was compared after one year of follow-up visit.Results After 8 weeks of intervention,the total clinical effective rate(95.56%)in the intervention group was significantly higher than that in the control group(82.22%)(χ^2 =4.05,P<0.05);At the same time,the YMRS score,SDS and SDSS scores of the two groups were significantly lower than those before the intervention(P<0.05 or P<0.01),and the decrease in the intervention group was more significant than that in the control group(P<0.05).After 1 year of follow-up visit,the recurrence rates in the intervention group and the control group were 17.78%(8/45)and 37.78%(17/45),respectively.The recurrence rate in the patients in the intervention group was significantly lower than that in the control group(χ^2 =4.49,P<0.05).Conclusion Comprehensive rehabilitation intervention is more effective in the patients with stable BAD.It can significantly improve manic and depressive symptoms,regulate the mood of patients,promote the recovery of social function,and reduce the recurrence rate.