胫前静脉途径多介入模式溶栓治疗急性下肢深静脉血栓的效果

Effect of multiple intervention modes via anterior tibial vein approach in the treatment of acute deep venous thrombosis of lower extremity

目的探讨胫前静脉途径多介入模式溶栓治疗急性下肢深静脉血栓的效果。方法选取2014年1月~2017年12月我院收治的90例急性下肢深静脉血栓患者作为研究对象,采取随机数字表法将其分成常规组以及实验组,每组各45例。常规组患者予以腘静脉置管溶栓治疗,实验组患者予以经胫前静脉途径多介入模式溶栓治疗。比较两组患者的血栓清除效果、并发症发生情况、住院时间以及随访情况。结果实验组患者的血栓清除效果优于常规组,差异有统计学意义(P<0.05)。实验组患者的并发症总发生率(4.44%)低于常规组(24.44%),差异有统计学意义(P<0.05)。实验组患者的住院时间短于常规组,差异有统计学意义(P<0.05);实验组患者的不良事件总发生率(2.22%)低于常规组(20.00%),差异有统计学意义(P<0.05)。结论急性下肢深静脉血栓患者采用胫前静脉途径多介入模式溶栓治疗可提升血栓清除效果,减少并发症的发生,缩短住院时间,降低不良事件发生率,值得临床广泛应用。

Objective To discuss the effect of multiple intervention modes via anterior tibial vein approach in the treatment of acute deep venous thrombosis of lower extremity.Methods A total of 90 patients with acute deep venous thrombosis of lower extremity from January 2014 to December 2017 treated in our hospital were chosen as research subjects.According to the random number table method,the patients were assigned to conventional group and test group,45 cases in each group.The conventional group took the thrombolytic therapy via popliteal vein approach;the test group took the multiple intervention modes via anterior tibial vein approach.The thrombosis removal effect,incidence of complications,hospital stay and follow-up results were compared.Results The thrombosis removal effect in the test group was better than that in the conventional group,with statistically significant difference(P<0.05).The total incidence rate of complications in the test group(4.44%)was lower than that in the conventional group(24.44%),with statistically significant difference(P<0.05).The hospital stay in the test group was shorter than that in the conventional group,with statistically significant difference(P<0.05).The total incidence rate of adverse events in the test group(2.22%)was lower than that in the conventional group(20.00%),with statistically significant difference(P<0.05).Conclusion For patients with acute deep venous thrombosis of lower extremity,the use of multiple intervention modes via anterior tibial vein approach can improve the thrombosis removal effect,reduce the incidence of complications,shorten the hospital stay,and reduce the incidence rate of adverse events,which is worthy of clinical application.