经纤维支气管镜支气管肺泡灌洗治疗支气管扩张合并肺部感染的效果评价

Evaluation of bronchoalveolar lavage through bronchoscopy in the treatment of bronchiectasis complicated with pulmonary infection

目的探究经纤维支气管镜支气管肺泡灌洗治疗支气管扩张合并肺部感染的效果。方法选取我院2016年3月~2018年3月收治的60例支气管扩张合并肺部感染的患者作为研究对象,采用随机数字表法分为对照组(30例)和观察组(30例),对照组进行常规治疗,观察组进行经纤维支气管镜支气管肺泡灌洗治疗,比较两组患者治疗总有效率、治疗前后血氧含量[血氧分压(PaO2)、血氧饱和度(SaO2)、PaO2/FiO2值]、康复治疗情况以及感染复发情况。结果观察组治疗总有效率高于对照组,差异有统计学意义(93.33%vs.73.33%,P<0.05);治疗3 d后,两组患者PaO2、SaO2和PaO2/FiO2高于治疗前,观察组上述指标高于对照组,差异有统计学意义(P<0.05);观察组发热时间、抗生素应用时间、住院时间短于对照组,半年内再就诊次数低于对照组,差异有统计学意义(P<0.05)。结论经纤维支气管镜支气管肺泡灌洗,对支气管扩张合并肺部感染患者的治疗效果佳,可以显著提高患者血氧含量,缩短治疗时间,值得进一步推广。

Objective To explore the effect of bronchoalveolar lavage through bronchoscopy in the treatment of bronchiectasis complicated with pulmonary infection.Methods From March 2016 to March 2018,60 patients of bronchiectasis complicated with pulmonary infection admitted to our hospital were selected as the subjects of study,they were divided into the control group(30 cases)and the observation group(30 cases)by random number table method,the control group was treated with routine treatment,and the observation group received bronchoalveolar lavage through bronchoscopy.The total effective rate of treatment,blood oxygen content(blood oxygen partial pressure[PaO2],blood oxygen saturation[SaO2],PaO2/FiO2 value)before and after treatment,the rehabilitation and recurrence of infection were compared between the two groups.Results The total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(93.33%vs.73.33%,P<0.05).After 3 days of treatment,the PaO2,SaO2 and PaO2/FiO2 of the two groups were higher than those before the treatment,the above indexes in the observation group were higher than those of the control group,the differences were statistically significant(P<0.05);the fever time,the antibiotic application time,the time of hospitalization were shorter than those of control group and the number of re visits within half a year was lower than that of the control group,the differences were statistically significant(P<0.05).Conclusion Bronchoalveolar lavage through bronchoscopy is a good treatment for bronchiectasis with pulmonary infection,it can significantly improve the blood oxygen content of the patients and shorten the time of treatment.It is worth further promoting.