鼓室注入盐酸氨溴索治疗分泌性中耳炎的临床效果

Clinical effect of tympanic injection of Ambroxol Hydrochloride in the treatment of secretory otitis media

目的探讨鼓室注入盐酸氨溴索治疗分泌性中耳炎的临床效果。方法选取2017年6月22日~2018年6月22日我院收治的120例分泌性中耳炎患者作为研究对象,按照抓阄随机化分组方法分为观察组(60例)与对照组(60例),对照组采用鼓室注入地塞米松治疗,观察组采用鼓室注入盐酸氨溴索治疗。比较两组患者的纯音听阈测定气导听力提高水平、语频气导听阈、鼓室压、并发症总发生率、总有效率。结果观察组0.5、1、2 kHz的纯音听阈测定气导听力提高水平高于对照组,差异均有统计学意义(P<0.05);观察组治疗后的语频气导听阈和鼓室压高于对照组,差异均有统计学意义(P<0.05);观察组的治疗总有效率高于对照组,并发症总发生率低于对照组,差异均有统计学意义(P<0.05)。结论对分泌性中耳炎患者实施鼓室注入盐酸氨溴索治疗效果显著,能够提高纯音听阈测定气导听力水平,降低并发症发生率,值得广泛推广。

Objective To explore the clinical effect of tympanic injection of Ambroxol Hydrochloride in the treatment of secretory otitis media.Methods A total of 120 patients with secretory otitis media treated in our hospital from June 22,2017 to June 22,2018 were selected as the research subjects.They were divided into observation group(n=60)and control group(n=60)according to the randomized method of drawing lots.Patients in the control group were treated with tympanic injection of dexamethasone,and in the observation group,they were treated with tympanic injection of Ambroxol Hydrochloride.The pure tone hearing threshold to measure the improvement of air conduction hearing level,speech frequency air conduction threshold,tympanic pressure,total complication rate,and total effective rate were compared in the two groups.Results The pure tone hearing thresholds to measure the improvement of air conduction hearing level in the observation group at 0.5,1 and 2 kHz were higher than those of the control group,and the differences were statistically significant(P<0.05).The speech frequency air conduction threshold and tympanic pressure of the observation group after treatment were higher than those of the control group,and the differences were statistically significant(P<0.05).The total therapeutic effective rate in the observation group was higher than that of the control group,and the total incidence of complications was lower than that of the control group with statistical significances(P<0.05).Conclusion The treatment of Ambroxol Hydrochloride in patients,with secretory otitis media has a remarkable effect.It can increase the pure tone hearing threshold to measure the level of air conduction hearing and reduce the incidence of complications,and is worthy of widespread promotion.