基于“五神脏”理论指导五心宁心汤从“心神”论治入睡困难型不寐临床研究

On the basis of the theory of “five gods and viscera” guidance of Wuxin Ningxin decoction from the “mind” of difficult sleep insomnia

目的:以五神脏理论为基础,指导和评价五心宁心汤治疗入睡困难型不寐病的临床疗效。方法:选取以入睡困难为主症的失眠障碍患者92例,将其随机分为对照组与治疗组各46例,两组患者均予音乐疗法配合穴位按摩治疗,及经颅磁刺激(TMS)治疗;治疗组在对照组治疗的基础上给予五心宁心汤口服,治疗7 d后根据两组患者的临床有效率、睡眠呼吸监测(PSG)结果、匹兹堡睡眠质量指数(PSQI)评分评价其临床疗效。结果:经治疗后两组临床有效率比较,治疗组、对照组总有效率分别为95.65%、84.78%,治疗组优于对照组,差异具有统计学意义(P<0.05);两组患者PSG监测的入睡时间、睡眠效率,PSQI量表评分比较,治疗组优于对照组,差异有统计学意义(P<0.05)。结论:五神脏理论指导下五心宁心汤治疗入睡困难型不寐病具有较好的效果。

Objective:Based on the theory of five gods and viscera,the clinical effect of Wuxin Ningxin decoction on insomnia was evaluated.Methods:Ninety-two patients with insomnia were randomly divided into control group(n=46) and treatment group(n=46).Both groups were treated with music therapy plus acupoint massage,transcranial magnetic stimulation(TMS),and the treatment group was treated with Wuxin Ningxin decoction after 7 days of treatment,the clinical efficacy,the result of PSG and PSQI score were observed to evaluate the clinical efficacy.Results:After treatment,the total effective rates of the two groups were 95.65% and 84.78% respectively,and the treatment group was superior to the control group(P<0.05).PSQI scale score comparison,the treatment group was superior to the control group,the difference was statistically significant(P<0.05).Conclusion:Wuxin Ningxin decoction under the guidance of the theory of five-shen-zang has certain effect on insomnia with difficulty in falling asleep.