探讨应用阿托伐他汀治疗亚急性硬膜下血肿的疗效及安全性

Investigation on the efficacy and safety of Atorvastatin in the treatment of subacute subdural hematoma

目的探讨阿托伐他汀治疗亚急性硬膜下血肿的临床效果。方法选取2017年3月~2019年3月我院收治的亚急性硬膜下血肿50例,根据数字奇偶法分为观察组与对照组,每组各25例。对照组予以颅骨下血肿最厚处钻孔处理,观察组予以阿托伐他汀治疗,比较两组治疗效果、不良反应与复发情况、神经功能评分、日常生活活动能力评分。结果观察组总有效率高于对照组,不良反应及复发率低于对照组,治疗后神经功能及日常生活活动能力评分低于对照组,差异有统计学意义(P<0.05)。结论在亚急性硬膜下血肿患者治疗中应用阿托伐他汀不仅疗效确切,而且可以减少不良反应发生,降低复发率,神经功能得到改善,日常生活活动能力得到提升,具有显著临床价值。

Objective To investigate the clinical effect of Atorvastatin in the treatment of subacute subdural hematoma.Methods A total of 50 patients with subacute subdural hematoma in our hospital from March 2017 to March 2019 were divided into the observation group and the control group according to the digital parity method,25 cases in each group.The control group was drilled at the thickest part of the skull hematoma,and the observation group was treated with Atorvastatin.The therapeutic effect,adverse reactions and recurrence,neurological function score and activity of daily life score of the two groups were compared.Results The total effective rate of the observation group was higher than that of the control group,the rates of adverse reactions and recurrence were lower than those of the control group,and the scores of neurological function and activities of daily life after treatment were lower than that of the control group,the differences were statistically significant(P<0.05).Conclusion Atorvastatin is not only effective in the treatment of subacute subdural hematoma,but also can reduce the incidence of adverse reactions,reduce the recurrence rate,improve the neurological function,and improve the ability of daily life,which has significant clinical value.