不同时机鼓室注射激素治疗全聋型突发性耳聋的临床效果比较

Clinical effect comparison of intratympanic hormone injection at different time in the treatment of total frequency type profound sudden sensorineural hearing loss

目的比较不同时机鼓室注射激素治疗全聋型突发性耳聋的临床效果。方法选取2014年2月~2019年1月我院收治的58例全聋型突发性耳聋患者作为研究对象,根据激素鼓室注射的时机不同分为Ⅰ组(27例)与Ⅱ组(31例)。Ⅰ组患者口服激素后即刻给予鼓室注射激素治疗,Ⅱ组患者口服激素1周后给予鼓室注射激素。比较两组患者的听觉阈值、治疗总有效率及并发症总发生率。结果两组患者治疗后的听觉阈值低于治疗前,差异有统计学意义(P<0.05);两组患者治疗后的听觉阈值比较,差异无统计学意义(P>0.05);两组患者的治疗总有效率及并发症总发生率比较,差异无统计学意义(P>0.05)。结论不同时机鼓室注射激素治疗全聋型突发性耳聋的临床效果相当,临床可根据患者的具体情况用药。

Objective To compare the clinical effect of intratympanic hormone injection at different time in the treatment of total frequency type profound sudden sensorineural hearing loss.Methods Fifty-eight patients with total frequency type profound sudden sensorineural hearing loss treated in our hospital from February 2014 to January 2019 were selected as the subjects.According to the random number table method,the patients were divided into groupⅠ(27 cases)and groupⅡ(31 cases).GroupⅠwas given intratympanic hormone injection immediately after oral administration,and groupⅡwas given intratympanic hormone injection one week after oral administration.The auditory threshold,total effective rate and total incidence of complications were compared between the two groups.Results The auditory threshold of the two groups after treatment were lower than those before treatment,the differences were statistically significant(P<0.05).There was no significant difference in auditory threshold between the two groups after treatment(P>0.05).There were no significant differences in the total effective rate and total incidence of complications between the two groups(P>0.05).Conclusion The clinical effect of intratympanic hormone injection at different time is similar for patients with total frequency type profound sudden sensorineural hearing loss,and it can be used according to the specific situation of patients.