趋化因子及其受体对卵巢癌发生发展的作用的研究进展

Research Progress on the Role of Chemokines and Their Receptors in the Development of Ovarian Cancer

卵巢癌是常见的生殖系统恶性肿瘤之一,由于卵巢癌发病早期多无症状,死亡率占各类妇科肿瘤之首。因此,寻找早期诊断卵巢癌的标志物意义重大。趋化因子是一类炎症介质,它们能够在多种肿瘤发生发展过程中发挥重要作用。本篇综述报道了趋化因子对卵巢癌发生发展的作用的研究进展。

Ovarian cancer is one of the common malignant tumors of the reproductive system.Because ovarian cancer is mostly asymptomatic in the early stages,the mortality rate is the highest in all types of gynecological tumors.Therefore,it is of great significance to find markers for early diagnosis of ovarian cancer.Chemokines are a class of inflammatory mediators,and they can play an important role in the development of many tumors.This review reports the research progress on the role of chemokines in the development of ovarian cancer.