泮托拉唑与奥美拉唑治疗消化性溃疡出血临床疗效比较

目的对比泮托拉唑与奥美拉唑治疗消化性溃疡出血的临床疗效。方法选取医院2018年3月至2019年6月收治的消化性溃疡出血患者100例,根据治疗方案的不同分为泮托拉唑组和奥美拉唑组,各50例。在常规治疗基础上,泮托拉唑组静脉滴注泮托拉唑钠40 mg,奥美拉唑组静脉滴注奥美拉唑钠40 mg,比较两组的临床疗效及不良反应发生情况。结果泮托拉唑组总有效率为96.00%,明显高于奥美拉唑组的90.00%(P<0.05);泮托拉唑组不良反应发生率为8.00%,明显低于奥美拉唑组的26.00%(P<0.05)。结论泮托拉唑和奥美拉唑治疗消化性溃疡出血均有效,泮托拉唑疗效更佳,不良反应更少。

Objective To compare the clinical effect of pantoprazole and omeprazole in the treatment of peptic ulcer bleeding.Methods From March 2018 to June 2019,100 patients with peptic ulcer bleeding were selected and divided into pantoprazole group and omeprazole group according to different treatment plans,50 cases in each group.On the basis of routine treatment,pantoprazole group was infused with 40 mg of pantoprazole sodium intravenously,omeprazole group was infused with 40 mg of omeprazole sodium intravenously.The clinical efficacy and adverse reactions of the two groups were compared.Results The total effective rate of pantoprazole group was 96.00%,which was significantly higher than 90.00%of omeprazole group(P<0.05).The incidence of adverse reactions in pantoprazole group was 8.00%,which was significantly lower than 26.00%of omeprazole group(P<0.05).Conclusion Pantoprazole and omeprazole are effective in the treatment of peptic ulcer bleeding,pantoprazole has better effect and fewer adverse reactions.