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糖皮质激素联合抗菌药物治疗肾脏风湿性疾病临床观察

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摘要 目的观察糖皮质激素联合抗菌药物治疗肾脏风湿性疾病的效果。方法选取医院2018年11月至2019年11月收治的肾脏风湿性疾病患者68例,采用奇、偶数平均分配法分为观察组和对照组,各34例。对照组单用抗菌药物治疗,观察组联用糖皮质激素。结果治疗后,两组肌酐清除率均明显升高,且观察组明显高于对照组(P<0.05);观察组总有效率为97.06%,明显高于对照组的82.35%(P<0.05)。结论糖皮质激素联合抗菌药物治疗肾脏风湿性疾病,可提高肌酐清除率和临床疗效。 Objective To observe the effect of glucocorticoid combined with antibiotics in the treatment of renal rheumatic diseases.Methods Totally 68 patients with renal rheumatic diseases admitted to the hospital from November 2018 to November 2019 were divided into the observation group and the control group by odd even average distribution method,34 cases in each group.The control group was treated with antibiotics alone,and the observation group was treated with glucocorticoids.Results After treatment,the creatinine clearance rate of the two groups was significantly higher than that before treatment that of the observation group was significantly higher than that of the control group(P<0.05),the total effective rate of the observation group was 97.06%,which was significantly higher than 82.35%of the control group(P<0.05).Conclusion Glucocorticoid combined with antibiotics can improve the creatinine clearance rate and clinical efficacy in the treatment of renal rheumatic diseases.
作者 郭秋君 乔丽
出处 《中国药业》 CAS 2019年第S02期26-27,共2页 China Pharmaceuticals
关键词 糖皮质激素 抗菌药物 肾脏风湿性疾病 肌酐清除率 临床疗效 glucocorticoid antibiotics renal rheumatic disease creatinine clearance rate clinical efficacy
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