化痰祛瘀法治疗泌乳素型垂体腺瘤的组方规律分析

Analysis of the Rules of the Prescription and Medication in the Treatment of Prolactin Type Pituitary Adenoma with the Method of Resolving Phlegm and Removing Blood Stasis

目的分析化痰祛瘀法治疗泌乳素型垂体腺瘤的组方用药规律。方法收集采用化痰祛瘀法治疗泌乳素型垂体腺瘤有效医案348例,运用中医传承辅助平台(V2.5)分析药物使用频次、关联规则和提取核心药物组合等。结果348张初诊处方中涉及66味中药,以垂宁方为化痰祛瘀法基本方,通过辨证配伍分析产生潜在新处方7张。结论通过TCMISS初步揭示了化痰祛瘀法为基本大法基础下,随证配伍治疗泌乳素型垂体腺瘤的处方用药规律,为总结课题组中医药临床用药经验提供客观方法,有助于为中医药治疗泌乳素型垂体腺瘤提供新的思路。

Objective To analyze the rules of the prescription of removing phlegm and blood stasis in the treatment of prolactin type pituitary tumor.Methods 348 cases of primary diagnosis of prolactin pituitary adenoma were collected,and the frequency of drug use,association rules and core drug combination were analyzed by using v2.5.Results 66 traditional Chinese medicines were involved in the first 348 prescriptions,and Suning formula was used as the basic formula of resolving phlegm and removing blood stasis.Conclusion Based on the basic method of resolving phlegm and removing blood stasis,this paper preliminarily reveals the rule of prescription medication of prolactin pituitary adenoma treated with syndrome compatibility,provides objective methods for summarizing the clinical medication experience of the research group,and helps to provide new ideas for the treatment of prolactin pituitary adenoma by TCM.