肾脏替代治疗患者残余肾功能的测量与评估

Evaluation of residual renal function in patients receiving renal replacement therapy

肾脏替代治疗(RRT)是急慢性肾功能损害患者重要治疗手段,在RRT下患者的残余肾功能(RRF)是影响患者预后的重要因素,而RRF的评估由于受RRT的影响存在一定困难,寻找新型指标显得很有必要,目前研究较多的指标包括胱抑素C(CysC),β2微球蛋白(β2-MG)及β踪迹蛋白(BTP)等。本文将结合近年来相关研究对RRT患者RRF评估进行综述。

Renal replacement therapy(RRT)is the most useful method for treatment of patients with acute or chronic renal dysfunction.In those undergoing RRT,the evaluation of residual renal function,which is a key factor affecting the patients’outcomes,is difficult due to RRT’effects.The present efforts have been made to investigate the value of using cystatin C(CysC),β-2 microglobulin(β2-MG)andβ-trace protein(BTP)for assessment of RRF.This article will summarize the recent progress in researches on RRF evaluation in patients receiving RRT.