摘要
目的探讨普拉洛芬滴眼液促进糖尿病视网膜病变(DR)患者瞳孔散大的作用。方法选取2016年2月至2016年9月期间于我院收治的双眼病变程度相当的DR患者112例,随机分成对照组和观察组,前者采用复方托吡卡胺滴眼液散瞳,后者采用复方托吡卡胺滴眼液联合普拉洛芬滴眼液散瞳,然后比较两组的散瞳效果。结果散瞳后观察组平均瞳孔面积(41.45±1.12)mm2,显著大于对照组(35.32±1.14)mm2,差异有统计学意义(t=5.81,P<0.05);观察组平均瞳孔散大面积(35.49±1.14)mm2,显著大于对照组(29.34±1.16)mm2,差异有统计学意义(t=5.10,P<0.05)。结论复方托吡卡胺滴眼液联合普拉洛芬滴眼液能够有效地促进DR患者瞳孔散大,为DR患者的临床诊治及随访提供了一种有效、简单且安全性高的散瞳方法。
Objective To study the clinical effects of pranoprofen eyedrops in promoting the pupil dilation for patients with diabetic retinopathy.Methods A total of 112 patients with diabetic retinopathy(similar severity of both eyes)admitted in our hospital from February 2016 to September 2016 were randomly divided into control group and observation group,and patients in the control group were given compound tropicamide eyedrops only,while patients in the observation group were given compound tropicamide eyedrops and pranoprofen eyedrops.The differences of pupil areas before and after dilation in the two groups were compared.Results After dilation,the average pupil area(41.45±1.12 mm2)of the observation group was significantly greater(35.32±1.14,t=5.81,P<0.05).Compared with the control group,the difference of pupil areas before and after dilation(35.49±1.14 mm2)in the observation group was significantly higher than that of the control group(29.34±1.16,t=5.10,P<0.05).Conclusions Compound tropicamide eye drops combined with Pranoprofen eyedrops is a simple,effective and safe method for dilating the pupils of patients with diabetic retinopathy.
作者
吴含春
WU Hanchun(Department of Ophthalmology,the Chinese Medicine Hospital of HeZe,HeZe 274000,China)
出处
《中国实用眼科杂志》
2018年第5期368-370,共3页
Chinese Journal of Practical Ophthalmology