强迫症患者一级亲属焦虑特点及其人格特点与患者焦虑情绪的相关性研究

Anxiety Characteristics of First-degree Relatives of Patients with Obsessive-compulsive Disorder and Correlation between Their Personality Characteristics and Anxiety of Patients

目的:探讨强迫症患者一级亲属焦虑特点及其人格特征与患者焦虑情绪的相关性。方法:选取2018年1月-2019年12月本院100例强迫症患者及其1名一级亲属作为强迫症组与亲属组,另选取同期在本院进行体检的100例健康人作为正常组。比较三组汉密尔顿焦虑量表(HAMA)与耶鲁-布朗强迫症状量表(Y-BOCS)评分;比较亲属组与正常组三维人格问卷(TPQ)评分;分析亲属组人格特征与强迫组焦虑症状的相关性。结果:强迫症组HAMA与Y-BOCS评分均高于亲属组和正常组(P<0.05)。亲属组HAMA与Y-BOCS评分均高于正常组(P<0.05)。亲属组在躲避伤害(HA)维度中悲观主义(HA1)和害怕不确定(HA2)因子评分明显高于正常组(P<0.05)。亲属组TPQ问卷中HA维度评分、依恋(RD3)因子评分与强迫组HAMA、Y-BOCS评分均呈正相关(P<0.05)。结论:强迫症患者一级亲属焦虑及强迫症状比正常人严重,且其人格特征中的躲避伤害及依恋与强迫症患者焦虑及强迫症状呈正相关。

Objective:To explore the anxiety characteristics of first-degree relatives of patients with obsessive-compulsive disorder and correlation between their personality characteristics and anxiety of patients Method:A total of 100 patients with obsessive-compulsive disorder and their one case first-degree relative of our hospital from January 2018 to December 2019 were selected as the obsessive-compulsive disorder group and the relative group,and 100 cases of healthy people underwent physical examination in our hospital during the same period were selected as the normal group.Hamilton anxiety scale(HAMA)and Yale-Brown compulsive symptom scale(Y-BOCS)among three groups were compared.The scores of three dimensional personality questionnaire(TPQ)were compared between the relative group and the normal group.The correlation between the personality characteristics of the relative group and the anxiety symptoms of the obsessive-compulsive disorder group was analyzed.Result:The scores of HAMA and Y-BOCS in the obsessive-compulsive disorder group were significantly higher than those of the relative group and the normal group(P<0.05).The scores of HAMA and Y-BOCS in the relative group were higher than those in the normal group(P<0.05).The scores of pessimism(HA1)and fear of uncertainty(HA2)in the harm avoidance(HA)dimension of the relative group were significantly higher than those in the normal group(P<0.05).HA dimension score and attachment(RD3)factor score in the TPQ questionnaire of the relative group was positively correlated with HAMA and Y-BOCS scores of the obsessive-compulsive disorder group(P<0.05).Conclusion:The anxiety and obsessive-compulsive symptoms of first-degree relatives of obsessive-compulsive patients were more serious than those of normal people,the harm avoidance and attachment in their personality characteristics is positively correlated with the anxiety and obsessive-compulsive of obsessive-compulsive patients.