钛基种植体表面涂层的研究进展

Research progress of Ti-implant surface coatings

钛基种植体是人体牙缺失修复治疗的理想修复装置,种植体周围软硬组织细菌性炎症和骨整合不良等是导致种植失败的常见原因。钛基种植体负载涂层可以抑制种植体周围细菌附着,促进成骨相关细胞增殖分化,从而提高种植体的性能以降低手术失败率。目前种植体涂层的种类繁多,该文对近年研究较多的抗菌涂层、促成骨涂层和抗菌-促成骨复合涂层的作用机制和优缺点进行综述。

Ti-implant is a kind of ideal restore device for tooth loss.The main culprit why many implant surgeries fail lies in bacterial inflammation and poor osseointegration of the hard and soft tissues surrounding the implants.So far,many studies have found that implants equipped with coatings,which are able to curb bacterial attachment and promote proliferation and differentiation of osteoblast,make longer the implants’duration of service accessible and reduce the failure rate of detal implant.Now there are various coatings in use.In this paper,the mechanism of action and the advantages and disadvantages of antibacterial coatings,osteogenic coatings and antibacterial-osteogenic composite coatings that are reported widely in recent years are summarized respectively.