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非酒精性脂肪肝纤维化评分、铁蛋白与冠心病的关系探讨 被引量:10

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摘要 目的探讨非酒精性脂肪肝纤维化评分、铁蛋白与冠心病严重程度的关系。方法选取2016年1月-2016年12月我院经腹部彩超诊断为非酒精性脂肪肝同时进行冠状动脉造影检查的住院病人200例,根据有无冠心病分为冠心病组(138例)与非冠心病组(62例)。计算其肝纤维化评分,根据造影结果行临床SYNTAX评分,并进行亚组分析。结果冠心病组血清铁蛋白、肝纤维化积分3~4级占比均高于非冠心病组(P<0.05)。高危组血清铁蛋白、肝纤维化3~4级占比均高于低危组(P<0.05);高危组血清铁蛋白、肝纤维化3~4级占比与中危组比较差异均无统计学意义(P>0.05)。结论非酒精性脂肪病人多出现血清铁蛋白增高,铁蛋白水平可以反映脂肪肝的严重程度,并且铁蛋白与冠心病的严重程度相关,非酒精性脂肪肝纤维化评分结合血清铁蛋白测定可以作为非酒精性脂肪肝病人冠心病高风险筛查的指标。
出处 《中西医结合心脑血管病杂志》 2020年第9期1503-1504,共2页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
基金 包头医学院校内基金项目(No.BYJJ-QM2016120)。
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  • 1William Nseir,Julnar Mograbi,Murad Ghali.Lipid-Lowering Agents in Nonalcoholic Fatty Liver Disease and Steatohepatitis: Human Studies[J]. Digestive Diseases and Sciences . 2012 (7)
  • 2European Association for the Study of the Liver,Ginès P,Angeli P,et al.EASL clinical practice guidelines on the man-agement of ascites,spontaneous bacterial peritonitis,and hepa-torenal syndrome in cirrhosis. Journal of Hepatology . 2010
  • 3D. Lebrec,J.P. Vinel,J.L. Dupas.Complications of portal hypertension in adults: a French consensus. European Journal of Gastroenterology and Hepatology . 2005
  • 4Adams LA,Lindor KD.Nonalcoholic fatty liver disease. Annals of Epidemiology . 2007
  • 5L.J. Melton.History of the Rochester Epidemiology Project. Mayo Clinic Proceedings . 1996
  • 6M Ekstedt,LE Franzén,UL Mathiesen,M Holmqvist,G Bodemar,S Kechagias.Statins in non-alcoholic fatty liver disease and chronically elevated liver enzymes: a histopathological follow-up study. Journal of Hepatology . 2007
  • 7A Uygun,A Kadayifci,AT Isik,T Ozgurtas,S Deveci,A Tuzun.Metformin in the treatment of patients with non-alcoholic steatohepatitis. Alimentary Pharmacology and Therapeutics . 2004
  • 8Ajamieh H,Farrell G,Wong HJ,et al.Atorvastatin protects obese mice against hepatic ischemia-reperfusion injury by Toll-like receptor-4suppression and endothelial nitric oxide synthase activation. Journal of Gastroenterology . 2012
  • 9Browning JD,Szczepaniak LS,Dobbins R,et al.Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology . 2004
  • 10Powell EE,Cooksley WG,Hanson R,et al.The natural history of nonalcoholic steatohepatitis: a follow-up study of forty-two patients for up to 21 years. Hepatology . 1990

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