上消化道癌内镜筛查192例恶性肿瘤临床病理探析

The Clinicopathological Analysis of 192 Cases of Malignant Tumors Screened by Upper Gastrointestinal Endoscopy

目的探析上消化道癌内镜筛查恶性肿瘤的临床病理。方法方便选取该县人民医院2011年1月-2017年12月进行上消化道癌内镜筛查的8 400例受检者,分析其病历资料与筛查结果。结果共检出胃高级别上皮内瘤变及癌变192例,检出率为2.29%;经计算,早诊率为76.56%,治疗率为87.50%,随访率为86.01%。男性检出恶性肿瘤130例,检出率为3.05%;女性检出恶性肿瘤62例,检出率为1.50%;男性的检出率高于女性,比较均差异有统计学意义(χ~2=5.256,P<0.05)。39~49岁的检出率为1.41%,50~59岁为2.52%,60~70岁为4.75%,3个年龄段对比,差异有统计学意义(χ~2=17.452,P<0.05)。结论上消化道癌内镜筛查联合病理活检对恶性肿瘤的检出率较高;上消化道癌的检出率和患者的性别及年龄有一定的相关性。

Objective To explore the clinicopathology of endoscopic screening for malignant tumors in upper gastrointestinal cancer. Methods Convenient selection of 8 400 patients who underwent endoscopic screening for upper gastrointestinal cancer from January 2011 to December 2017 were selected and their medical records and screening results were analyzed.Results 192 cases of high-grade intraepithelial neoplasia and carcinogenesis of stomach were detected, the detection rate was 2.29%. By calculation, the early diagnosis rate was 76.56%, the treatment rate was 87.50%, and the follow-up rate was86.01%. Males detected 130 cases of malignant tumors, the detection rate was 3.05%;females detected 62 cases of malignant tumors, the detection rate was 1.50%;the detection rate of males was higher than that of females,and the difference was statistically significant(χ~2=5.256, P<0.05). The detection rates of 39-49 years old, 50-59 years old and 60-70 years old were 1.41%, 2.52% and 4.75%, respectively. There was statistically significant difference among the three age groups(χ~2=17.452, P <0.05). Conclusion The detection rate of malignant tumors in upper gastrointestinal cancer by endoscopic screening combined with pathological examination is higher, and the detection rate of upper gastrointestinal cancer is related to the sex and age of patients.