放大内镜结合窄带成像下微腺管密度对胃早期肿瘤性病变的诊断价值

Diagnostic Value of Microtubule Density under Magnifying Endoscopy Combined with Narrow Band Imaging in Early Gastric Neoplastic Lesions

目的研究放大内镜联合窄带成像(ME-NBI)下微腺管密度对于胃早期肿瘤性病变患者的作用与效果。方法方便选取该院收治的40例疑似胃早期肿瘤性病变患者,纳入时间为2019年1-10月,对全部患者都施予胃镜检测,观察比较其结果。结果白光内镜在实施检测后,其敏感度、特异度、阳性预测值(PPV)、阴性预测值(NPV)依次就是75.86%、63.08%、59.09%、84.72%。ME-NBI系统在实施检测后,其敏感度、特异度、PPV、NPV依次就是96.55%(χ~2=5.220,P=0.022)、81.54%(χ~2=5.532,P=0.019)、85.71%(χ~2=4.539,P=0.033)、95.45%(χ~2=4.351,P=0.037)。ME-NBI在检测后其敏感度大于白光内镜(P<0.05)。血管与表面结构(VS)分型在检测后其敏感度、特异度、PPV、NPV依次就是79.31%、73.85%、65.22%、85.92%。VS分型联合IP比值在检测后其敏感度、特异度、PPV、NPV依次就是96.55%(χ~2=4.062,P=0.044)、87.69%(χ~2=4.011,P=0.045)、85.71%(χ~2=4.324,P=0.038)、96.97%(χ~2=5.230,P=0.022)。VS分型联合IP比值在检测后其敏感度大于VS分型(P<0.05)。结论对于胃早期肿瘤性病变患者来说,ME-NBI能够得到十分良好且确定的诊断效果,可推广。

Objective To study the effect of microtubule density under magnifying endoscopy combined with narrow band imaging(ME-NBI) on patients with early gastric neoplastic lesions. Methods 40 patients of suspected early gastric neoplastic lesions were convenienty enrolled in the hospital. From January 2019 to October 2019, all the patients were examined by gastroscopy, the results were observed and compared. Results After white light endoscopy was tested, its sensitivity, specificity, positive predictive value(PPV), negative predictive value(NPV) were 75.86%, 63.08%, 59.09%, and84.72%, respectively. After the implementation of detection, the sensitivity, specificity, PPV and NPV of me-nbi system are96.55%(χ~2=5.220, P=0.022), 81.54%(χ~2=5.532, P =0.019), 85.71%(χ~2=4.539, P =0.033), and 95.45%(χ~2=4.351, P =0.037).After detection, the sensitivity of me-nbi was higher than that of white light endoscopy(P<0.05). The sensitivity, specificity,PPV and NPV of vessel and surface structure(VS) classification were 79.31%, 73.85%, 65.22% and 85.92%, respectively.The sensitivity, specificity, PPV, and NPV of the combined IP ratio of VS classification were 96.55%(χ~2=4.062, P=0.044),87.69%(χ~2=4.011, P=0.045), 85.71%(χ~2=4.324, P=0.038), and 96.97%(χ~2=5.230, P=0.022). After detection, the combined IP ratio of VS typing was more sensitive than that of VS typing(P<0.05). Conclusion for patients with early gastric neoplasia,me-nbi can achieve very good and definite diagnostic effect, which can be extended.