放疗同步化疗治疗宫颈癌的临床效果

Clinical Effect of Concurrent Radiotherapy and Chemotherapy on Cervical Cancer

目的研究放疗同步化疗治疗宫颈癌的临床效果。方法方便选择该院2017年3月-2019年8月收治的40例宫颈癌患者,数字表法随机分组,对照组进行调强适形放疗,实验组放疗同步化疗,对比治疗效果和不良反应。结果实验组治疗总有效率95.00%高于对照组的70.00%,结果对比差异有统计学意义(χ~2=4.330,P=0.030);实验组1年生存率90.00%高于对照组的70.00%,局部复发率15.00%低于对照组的35.00%,远处转移率10.00%低于对照组的25.00%,结果对比差异有统计学意义(P<0.05);实验组白细胞减少,血红蛋白降低,恶心呕吐,纳差乏力等不良反应发生率高于对照组,结果对比差异有统计学意义(P<0.05)。结论放疗同期使用化疗药物对宫颈癌有显著疗效。

Objective To study the clinical effect of concurrent radiotherapy and chemotherapy on cervical cancer.Methods Convenient select 40 cervical cancer patients who were treated in the department from March 2017 to August 2019 were randomly divided into groups according to the digital table method. The control group received intensity-modulated conformal radiotherapy and the experimental group received concurrent radiotherapy for chemotherapy. The treatment effects and adverse reactions were compared. Results The total effective rate of treatment in the experimental group was 95.00% higher than 70.00% in the control group. The difference was statistically significant(χ~2=4.330, P=0.03).The one-year survival rate of the experimental group was 90.00% higher than the control group’s 70.00%, The local recurrence rate was 15.00% lower than the control group’s 35.00%, and the distant metastasis rate was 10.00% lower than the control group’s 25.00%. The difference was statistically significant(P<0.05);the experimental group had reduced white blood cells and reduced hemoglobin. The incidence of adverse reactions such as nausea, vomiting, and fatigue was higher than that of the control group, The difference was statistically significant(P <0.05). Conclusion Concomitant use of chemotherapeutic drugs in radiotherapy has a significant effect on cervical cancer.