丹参多酚注射液联合丁苯酞注射液治疗脑梗死患者的效果对比

Effect Comparison of Salvia Polyphenol Injection Combined with Butylphthalide Injection in Patients with Cerebral Infarction

目的浅析在脑梗死患者的对症治疗中,应用丁苯酞注射液合丹参多酚注射液的治疗可行性。方法方便选取80例于2018年1月—2019年8月因脑梗死疾病入该院接受诊疗的患者,行分组对比论证。一组采用丁苯酞注射液治疗,40例作丁苯酞组;另一组在此基础上加以注射用丹参多酚酸盐联合治疗,同40例作丹参多酚组。比较两组治疗前后认知功能、神经功能、不良反应及日常生活质量。结果经治疗,丹参多酚组MoCA评分、NIHSS评分及ADL评分显著优于丁苯酞组(t=4.718、-7.473、13.308,P<0.05);丹参多酚组不良反应总发生率12.50%,丁苯酞组7.50%,差异无统计学意义(χ^2=1.389,P=0.239>0.05)。结论脑梗死疾病推荐应用丁苯酞注射液合注射用丹参多酚酸盐对症治疗,可有效促患者认知功能恢复,并改善患者神经功能,促日常生活质量提升,临床用药安全性可。

Objective To analyze the feasibility of using butylphthalide injection and danshen polyphenol injection in the symptomatic treatment of patients with cerebral infarction.Methods A total of 80 patients who were admitted to the hospital for diagnosis and treatment of cerebral infarction from January 2018 to August 2019 were convenient selected and screened for group comparison.One group was treated with butylphthalide injection,40 cases were used as butylphthalide group;one group was combined with salvia polyphenolate for injection,and the same group was used as salvia polyphenol group.Cognitive function,neurological function,adverse reactions,and quality of daily life were compared between the two groups before and after treatment.Results After treatment,the MoCA score,NIHSS score,and ADL score of the salvia polyphenol group were significantly better than those of the butylphthalide group t=4.718,-7.473,13.308,P=0.000>0.05;the total incidence of adverse reactions in salvia polyphenol group was 12.50%,Butylphthalide group 7.50%,and the difference was statistically significant(χ^2=1.389,P=0.239<0.05).Conclusion The symptomatic treatment of stilbenephthalein injection and salvia polyphenolate for injection is recommended for the treatment of cerebral infarction,which can effectively promote the recovery of patients'cognitive function,improve the neurological function of patients,promote the improvement of daily life quality,and the safety of clinical medication is worthwhile.