缺血性脑卒中与颈动脉斑块新生血管及血清胱抑素C的相关性

The Correlation between Ischemic Stroke and Carotid Plaque Neovascularization and Serum Cystatin C

目的分析缺血性脑卒中与颈动脉斑块新生血管及血清胱抑素C的相关性。方法该文研究对象为方便选取缺血性脑卒中患者,总例数为100例作为观察组,再选取100名健康体检者作为对照组,收取时间在2017年2月-2018年2月之间,使用超声造影检测颈动脉斑块新生血管,测定血清胱抑素C,将血清胱抑素C水平、颈动脉斑块新生血管情况进行对比。结果观察组新生血管等级(Ⅰ级2例、Ⅱ级26例、Ⅲ级31例、Ⅳ级20例)和对照组相比,两者之间差异有统计学意义(χ~2=5.674、14.881、18.714、14.198,P<0.05);观察组血清胱抑素C水平(1.05±0.82)mg/L与对照组血清胱抑素C水平(0.82±0.12)mg/L相比,差异有统计学意义(t=2.775,P<0.05)。结论缺血性脑卒中与颈动脉斑块新生血管及血清胱抑素C之间具有密切相关性,可能预示着缺血性脑卒中发生。

Objective To analyze the correlation between ischemic stroke and carotid plaque neovascularization and serum cystatin C. Methods The subjects in this article are Convenient selected patients with ischemic stroke. The total number of cases is 100 as the observation group, and another 100 healthy people are selected as the control group. The collection time is between February 2017 and February 2018. Carotid plaque neovascularization was detected, serum cystatin C was measured, and serum cystatin C level and carotid plaque neovascularization were compared. Results Observation group level of new blood vessels(Ⅰ level 2 cases, Ⅱ level 26 cases, 31 cases Ⅲ, Ⅳ level 20 cases) and control group compared,the difference was statistically significant between the two groups(χ~2=5.674,14.881,18.714,14.198,P<0.05);the serum cystatin C level(1.05±0.82)mg/L in the observation group was statistically significantly different from that in the control group(0.82 ±0.12)mg/L(t =2.775,P <0.05). Conclusion There is a close correlation between ischemic stroke and carotid plaque neovascularization and serum cystatin C, which may indicate the occurrence of ischemic stroke.