Nd:YAG激光联合牙周基础治疗对慢性牙周炎患牙龈沟液中sICAM-1的影响分析

Effect of Nd:YAG Laser Combined with Periodontal Therapy on sICAM-1 in Gingival Crevicular Fluid in Patients with Chronic Periodontitis

目的分析慢性牙周炎患者使用Nd:YAG激光联合牙周基础治疗对于患者牙龈沟液中sICAM-1的影响效果。方法选择2018年4—12月进入该院接受治疗的60例患者作为研究对象,使用随机数字法分为观察组(30例患者,78颗患牙)和对照组(30例患者,76颗患牙),对照组患者采用牙周基础治疗,观察组患者采用Nd:YAG激光联合牙周基础治疗,观察对比患者在治疗后的牙龈沟液中sICAM-1含量和牙周临床指数。结果观察组患者的牙龈沟液中sICAM-1的含量(162.47±35.78)ng/mL要少于对照组(186.35±36.75)ng/mL,两组比较差异有统计学意义(t=5.157,P<0.05);观察组患者的牙周临床指数也要好于对照组,两组结果比较差异有统计学意义(P<0.05)。结论慢性牙周炎患者使用Nd:YAG激光联合牙周基础治疗可以降低患者牙龈沟液中sICAM-1的含量,减轻患者的牙周炎病情,牙龈沟液中sICAM-1的含量可以用于评价牙周状态的指标。

Objective To analyze the effect of sICAM-1 in gingival crevicular fluid of patients with chronic periodontitis using Nd:YAG laser combined with periodontal basic therapy.Methods A total of 60 patients who were admitted to the hospital for treatment from April to December 2018 were selected as the research objects.They were divided into observation group(30 patients,78 teeth)and control group(30 patients,76 teeth)using random number method,the patients in the control group were treated with periodontal basic treatment,the patients in the observation group were treated with Nd:YAG laser combined with periodontal basic treatment,and the sICAM-1 content and periodontal clinical index of the patients after treatment were observed and compared.Results The content of sICAM-1 in the gingival crevicular fluid of the observation group(162.47±35.78)ng/mL was less than that of the control group(186.35±36.75)ng/mL.The difference between the two groups was statistically significant(t=5.157,P<0.05);The periodontal clinical index of patients in the observation group was also better than that in the control group,and there was a statistically significant difference between the two groups(P<0.05).Conclusion The use of Nd:YAG laser combined with periodontal basic therapy in patients with chronic periodontitis can reduce the content of sICAM-1 in patients with gingival crevicular fluid and reduce the periodontitis of patients.The content of sICAM-1 in gingival crevicular fluid can be used for evaluation Indicator of periodontal state.