新型冠状病毒肺炎多代聚集性病例流行特征调查

Epidemiological characteristics of multi-generation clustered cases of COVID-19

目的掌握COVID-19多代聚集性病例相关特征,对河南省报告的多代聚集性病例进行流行病学描述和分析。方法选取截至2020年2月23日突发公共卫生事件管理信息系统中河南省上报的COVID-19传播代次≥3代的聚集性疫情。分析包括:①病例的基本特征;②地区分布、时间分布、临床类型分布;③疾病的潜伏期。结果河南省内多代聚集性病例占河南省内所有确诊病例数的9.05%,且普通型(51.54%)和轻型病例(23.08%)占比较高。河南省内多代聚集性病例占其所在地确诊病例比例最高可达60.38%,报告起数最多有4起。病例代次多集中在2代(58.46%)、3代(23.85%)病例。发病至确诊时间间隔随着代次的增加逐渐下降。高年龄组(>65岁)人群危重症比例(42.86%)最高。潜伏期中位数为5 d。结论COVID-19潜伏期长,传播力强且潜伏期具有传染性,因此聚集性疫情是防控的关键。对多代聚集性病例的分析和了解,可以在一定程度上,对即将复工复学形成的人员聚集的动态防控提供一定的指导作用。

Coronavirus disease 2019(COVID-19)has strong infectious power,and multi-generation clustered cases are easier to be appearing.To understand the relevant characteristics of multi-generation clustered cases of COVID-19,the epidemiological description and analysis of multi-generation clustered cases reported in Henan province were performed.The clustered epidemics of COVID-19 with more than 3 generation were selected from the public health emergency management information system of Henan province,as of February 23,2020.The basic characteristic of cases;regional distribution,time distribution,clinical type distribution and incubation period were analyzed.Results:Multi-generation clustered cases accounted for 9.05%of all confirmed cases in Henan province,in addition,common and light cases accounted for a relatively high proportion,with 51.54%and 23.08%respectively.All of the multi-generation clustered cases in Henan province accounted for 60.38%of confirmed cases in its district,with a maximum of 4 reported clustered outbreaks.The number of cases was mostly concentrated on the second generation(58.46%)and the third generation(23.85%).The interval from onset to diagnosis was gradually decreased with the increase of generations.The high age group(>65 years)accounts for highest proportion(42.86%)in cases with critical illness.Median incubation period is 5 d.COVID-19 has a long incubation period,strong infectious power and infectivity during incubation period,so the cluster epidemic is the key to prevent and control.The analysis and understanding of multi-generation clustered cases can,to a certain extent,provide a certain guidance for the dynamic prevention and control of the gathering of personnel who will return to work and school.