布地奈德/福莫特罗粉剂联合噻托溴铵治疗稳定期慢阻肺合并糖尿病的疗效分析

Analysis of the Efficacy of Budesonide/Formoterol Powder Combined with Tiotropium Bromide in the Treatment of Stable COPD with Diabetes

目的探究布地奈德/福莫特罗粉剂联合噻托溴铵治疗稳定期慢阻肺合并糖尿病的治疗效果。方法对该院2017年6月-2019年1月期间诊治的88例稳定期慢阻肺合并糖尿病患者进行病情回顾分析,在患者及其家属同意后,将其平均分组为观察组、对照组,每组44例患者。对照组患者分组期采用布地奈德联合福莫特罗粉剂进行治疗,观察组患者在对照组用药的基础上加服噻托溴铵进行治疗。分组治疗结束后,医护人员将其治疗有效率、治疗前后空腹血糖值、餐后血糖值与并发症机率进行分析研究。结果观察组与对照组患者治疗有效率分别为(97.7%)、(84.0%),差异有统计学意义(χ^2=3.577,P<0.05);治疗前,两组患者各阶段血糖值,差异无统计学意义(χ^2=0.330、0.618,P=0.091、0.068>0.05),治疗后,观察组患者空腹血糖值与餐后2 h血糖值均优于对照组患者,差异有统计学意义(χ^2=4.665、5.007,P<0.05);观察组与对照组患者并发症发生率分别为2.2%、9.0%,差异有统计学意义(χ^2=5.378,P<0.05)。结论布地奈德/福莫特罗粉剂联合噻托溴铵能够有效提高稳定期慢阻肺合并糖尿病患者的治疗有效率,降低并发症发生率并改善其空腹血糖值与餐后血糖值情况,治疗效果极佳。

Objective To explore the therapeutic effect of budesonide/formoterol powder combined with tiotropium bromide in the treatment of stable COPD with diabetes.Methods A retrospective analysis was performed on 88 patients with stable COPD and diabetes diagnosed and treated during June 2017 to January 2019 in the hospital.After the patients and their families agreed,they were divided into observation group and control group.There were 44 patients in each group.Patients in the control group were treated with budesonide combined with formoterol powder during the grouping period.Patients in the observation group were treated with tiotropium bromide on the basis of medications in the control group.After the end of the group treatment,the medical staff analyzed the treatment efficiency,fasting blood glucose value before and after treatment,postprandial blood glucose value and the probability of complications.Results The treatment efficiency of the observation group and the control group were(97.7%)and(84.0%),respectively(χ^2=3.577,P<0.05);before treatment,there was no significant difference in blood glucose values between the two groups of patients(χ^2=0.330,0.618,P=0.091,0.068>0.05),after treatment,the fasting blood glucose value and 2 h postprandial blood glucose value of the observation group were better than those of the control group(χ^2=4.665,5.007,P<0.05);the complications of the observation group and the control group were(2.2%),(9.0%)(χ^2=5.378,P<0.05).Conclusion Budesonide/formoterol powder combined with tiotropium bromide can effectively improve the treatment efficiency of stable COPD patients with diabetes,reduce the probability of complications,and improve their fasting blood glucose and postprandial blood glucose.The effect is very good.