丙酸氟替卡松气雾剂吸入治疗小儿肺炎支原体感染所致慢性咳嗽的临床效果分析

Clinical Effect of Fluticasone Propionate Aerosol In halation on Chronic Cough Caused by Mycoplasma Pneumoniae Infection in Children

目的研究丙酸氟替卡松气雾剂吸入治疗方案用于肺炎支原体感染引发慢性咳嗽患儿的临床药物治疗效果。方法对2017年3月-2019年4月该院治疗的62例肺炎支原体感染引发慢性咳嗽患儿开展这次数据统计,分组手段选用随机数字表法,不同组别收入31例,试验组采取阿奇霉素干混悬剂服用治疗+丙酸氟替卡松气雾剂吸入治疗方案,对照组采取阿奇霉素干混悬剂服用治疗方案,对不同组别治疗有效总占比、咳嗽症状得以缓解时长、肺处啰音消除所用时长、用药期间严重症状出现总次数、患儿家长治疗满意总占比予以比对。结果试验组治疗有效总占比较对照组计算指标结果增加(96.77%vs 77.42%),差异有统计学意义(χ^2=5.166,P=0.023<0.05);试验组咳嗽症状得以缓解时长、肺处啰音消除所用时长、用药期间严重症状出现总次数较对照组计算指标结果减少[(118.60±8.65)h、(6.41±1.20)d、(2.50±0.37)次vs (229.54±9.10)h、(9.80±2.47)d、(4.98±0.60)次],差异有统计学意义(t=49.197、6.873、19.588,P=0.000、0.000、0.000<0.05);试验组患儿家长治疗满意总占比较对照组计算指标结果增加(96.77%vs 80.65%),差异有统计学意义(χ^2=4.026,P=0.044<0.05)。结论为肺炎支原体感染引发慢性咳嗽患儿应用丙酸氟替卡松气雾剂吸入治疗方案展示出较优临床药物治疗效果。

Objective To study the clinical effect of fluticasone propionate aerosol inhalation treatment regimen on children with chronic cough caused by mycoplasma pneumoniae infection. Methods This data was collected from 62 children with chronic cough caused by Mycoplasma pneumoniae treated in the hospital from March 2017 to April 2019.The random number table method was used as the grouping method. 31 cases were included in each group. The experimental group took azithromycin dry suspension treatment + fluticasone propionate aerosol inhalation treatment regimen, and the control group took azithromycin dry suspension administration treatment regimen. The total effective proportion of treatment in different groups, the duration of cough symptom relief, the duration for the elimination of rales at the lungs, the total number of severe symptoms during the medication period, and the total proportion of parents’ satisfaction with treatment were compared. Results The experimental group’s total treatment effectiveness accounted for an increase in the calculated index results compared with the control group(96.77% vs 77.42%), and the differences was statistically significant(χ^2=5.166, P =0.023 <0.05);cough symptoms in the experimental group were alleviated, duration of elimination of rales at the lungs, and the total number of severe symptoms during the medication period were reduced compared with the results calculated in the control group [(118.60 ± 8.65) h,(6.41 ± 1.20) d,(2.50± 0.37) times vs(229.54 ± 9.10) h,(9.80 ± 2.47) d,(4.98 ± 0.60) times], the difference was statistically significant(t=49.197, 6.873, 19.588, P =0.000, 0.000, 0.000 <0.05);the total treatment satisfaction of children’s parents increased compared with that of the control group(96.77% vs 80.65%), and the differences was statistically significant(χ^2= 4.026,P=0.044 <0.05). Conclusion Fluticasone propionate aerosol inhalation therapy for children with chronic cough caused by Mycoplasma pneumoniae infection has shown better clinical drug treatment effect.